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Movie Explores The Impact Of Breast Cancer On Patients And Loved Ones

I caught this movie last week flipping though channels looking for something to watch while I knitted.

Five” stars Patricia Clarkson, Rosario Dawson, Lyndsy Fonseca, Ginnifer Goodwin, Josh Holloway, Tony Shalhoub, Jeffrey Tambor, and Jeanne Tripplehorn.  It is an anthology of five short films exploring the impact of breast cancer on people’s lives.

The first one, the story of Charlotte (Ginnifer Goodwin), is set in 1969.  Charlotte lays dying in her bedroom while the family mills around the house and the TV showing the mans first step on the moon.  Her story for me was taken over by the effect of her cancer on her young daughter Pearl who only wants to see her mom.   Finally she manages to sneak into the room.

The second one is Mia’s story.  Mia (Patricia Clarkson) is the tale of Read more »

*This blog post was originally published at Suture for a Living*

Still No Consensus On Optimal Treatment For Ductal Carcinoma In Situ (DCIS)

Ductal Carcinoma in Situ (DCIS) in the breast, histopathology w/ hematoxylin & eosin stain, Wiki-Commons image

More, a magazine “for women of style & substance,” has an unusually thorough, now-available article by Nancy F. Smith in its September issue on A Breast Cancer You May Not Need to Treat.

The article’s subject is DCIS (Ductal Carcinoma in Situ). This non-invasive, “Stage 0” malignancy of the breast has shot up in reported incidence over the past two decades. It’s one of the so-called slow-growing tumors detected by mammography; a woman can have DCIS without a mass or invasive breast cancer.

While some people with this diagnosis choose to have surgery, radiation or hormonal treatments, others opt for a watchful waiting strategy. The article quotes several physicians, including oncologists, who consider Read more »

*This blog post was originally published at Medical Lessons*

When Age Plays A Role In Medical Decision-Making

Missed Diagnosis Lawsuit and the Dynamics of Age Related to Risk

Years ago I had the opportunity to care for Mr Smith, a 101 year old man who presented to the hospital with chest pain and shortness of breath. Besides having  101 year old heart and lungs that tend to follow their own  biological clock,  this man also had a massive chest tumor filling 85% of one side of his thorax.

Whoah really?  What does that mean in a 101 year old man?  Most folks this age have exceeded the normal bell curve distribution of life and disease.  When you reach 101 years old, there isn’t a lot of chronic anything you can catch with the expected time you have left on earth.

Every now and then, however, we find patients who are the exception to the rule, such as the 101 year old guy that present with a new cancer diagnosis.  That’s where being an internist comes in handy. Read more »

*This blog post was originally published at The Happy Hospitalist*

FDA Approves A New, Monoclonal Antibody For Lymphoma

Hodgkin's Disease pathology image shows classic "Reed-Sternberg" cell in center, W-C image Recently, the FDA announced its approval, upon accelerated review, of a new drug, Adcetris (brentuximab) for patients with Hodgkin’s lymphoma that has relapsed after bone marrow transplant and for some patients with T-cell anaplastic large cell lymphoma (ALCL).

This interests me for a lot of reasons, among them that I used to work in the field of lymphoma immunology and spent some time in my life studying molecules like CD30, the protein to which the new antibody binds.

First, a mini-primer on the disease and numbers of patients involved: Read more »

*This blog post was originally published at Medical Lessons*

Oncologist Considers Heat-Based Cancer Treatment

There’s so much weird and exciting cancer news this week, it’s hard to keep up!

Double-kudos to Andrew Pollack on his front-page and careful coverage in the New York Times of the hyperthermic intraperitoneal chemotherapy (Hipec) technique that’s being used at some name-brand health care facilities to treat colon cancer.

First, he spares no detail in the Times describing the seemingly primitive, crude method:

….For hours on a recent morning at the University of California, San Diego, Dr. Andrew Lowy painstakingly performed the therapy on a patient.

After slicing the man’s belly wide open, Read more »

*This blog post was originally published at Medical Lessons*

Latest Interviews

IDEA Labs: Medical Students Take The Lead In Healthcare Innovation

It’s no secret that doctors are disappointed with the way that the U.S. healthcare system is evolving. Most feel helpless about improving their work conditions or solving technical problems in patient care. Fortunately one young medical student was undeterred by the mountain of disappointment carried by his senior clinician mentors…

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How To Be A Successful Patient: Young Doctors Offer Some Advice

I am proud to be a part of the American Resident Project an initiative that promotes the writing of medical students residents and new physicians as they explore ideas for transforming American health care delivery. I recently had the opportunity to interview three of the writing fellows about how to…

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Latest Book Reviews

Book Review: Is Empathy Learned By Faking It Till It’s Real?

I m often asked to do book reviews on my blog and I rarely agree to them. This is because it takes me a long time to read a book and then if I don t enjoy it I figure the author would rather me remain silent than publish my…

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The Spirit Of The Place: Samuel Shem’s New Book May Depress You

When I was in medical school I read Samuel Shem s House Of God as a right of passage. At the time I found it to be a cynical yet eerily accurate portrayal of the underbelly of academic medicine. I gained comfort from its gallows humor and it made me…

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Eat To Save Your Life: Another Half-True Diet Book

I am hesitant to review diet books because they are so often a tangled mess of fact and fiction. Teasing out their truth from falsehood is about as exhausting as delousing a long-haired elementary school student. However after being approached by the authors’ PR agency with the promise of a…

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