April 13th, 2011 by Medgadget in News, Research
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IBM and the Institute of Bioengineering and Nanotechnology in Shanghai have designed a new type of polymer that can detect and destroy antibiotic-resistant bacteria such as MRSA. The polymer nanostructures also prevent bacteria from developing drug resistance. Moreover, because of the mechanism by which the nanostructures work, they don’t affect circulating blood cells, and, unlike most traditional antimicrobial agents, the nanostructures are biodegradable, naturally eliminated from the body rather than remaining behind and accumulating in tissues.
From the Nature Chemistry abstract by Nederberg, et al.: Read more »
*This blog post was originally published at Medgadget*
March 19th, 2011 by Jennifer Wider, M.D. in News, Research
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National Women and Girls AIDS Awareness Day, a nationwide observance that raises awareness and promotes action in the fight against HIV/AIDS, took place on March 10. As the nation turns its attention to this important cause, women and girls around the world continue to be affected by HIV/AIDS in high numbers. According to reports from the Joint United Nations Program on HIV/AIDS, HIV is the leading cause of death and disease among women of reproductive age across the globe.
HIV is a virus that can cause acquired immunodeficiency syndrome, or AIDS, a disease that diminishes the body’s ability to fight off infection. Unprotected intercourse is the primary way HIV is spread, but it can also be shared through IV drug use, blood transfusion or from mother to baby during pregnancy, childbirth or breastfeeding.
Despite the fact that HIV/AIDS-related deaths are significantly lower in the United States when compared with other regions of the world, the disease remains a serious public health issue. According to statistics from the Centers of Disease Control and Prevention (CDC) in Atlanta, roughly 280,000 women are affected by AIDS in the United States today. Read more »
*This blog post was originally published at Society for Women's Health Research (SWHR)*
March 6th, 2011 by Paul Auerbach, M.D. in Better Health Network, Health Tips
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This is a guest post by Dr. Erik McLaughlin.
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Traveler’s Diarrhea: The Basics
Known around the world by many names including “Montezuma’s revenge,” “Delhi belly” and “mummy tummy,” traveler’s diarrhea (TD) is the most common illness faced by travelers. Nothing can slow down a fun trip as easily as TD — and it can also have serious health implications. TD typically lasts four to six days, and 90 percent of cases occur within the first two weeks of travel.
Anatomy You Need to Know
The gastrointestinal tract starts at the mouth and ends at the anus. After food enters the mouth, it passes through the esophagus to the stomach, where it sits for approximately 45 minutes. After being broken down by gastric secretions, food matter enters the small intestine (duodenum, jejunum, and ileum in order). The small intestine is the site where most nutrients are absorbed by the body. From the small intestine, food matter begins to look more like feces as it progresses to the large intestine or colon. The colon absorbs water from the food material before the material passes through the anus and exits the body as feces.
Symptoms
Recognizing the warning signs of TD, such as blood in the stool, fever, or abdominal cramping, can help a savvy traveler know when to seek medical help.
TD has many definitions; the presence of three or more loose-formed stools in one day is a good one. Abdominal cramping, nausea, vomiting and fever may also occur. The presence of blood in the stool can indicate that infection has directly damaged the intestinal wall and should be taken seriously. Read more »
This post, Traveler’s Diarrhea: The Basics, was originally published on
Healthine.com by Paul Auerbach, M.D..
March 3rd, 2011 by RyanDuBosar in Health Policy, Research
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High rates of inappropriate antibiotic use continued despite a 15-year campaign by the Centers for Disease Control and Prevention (CDC) aimed at Michigan physicians and consumers on the dangers of antibiotic overuse.
The Center for Healthcare Research & Transformation (CHRT) released an issue brief detailing overall antibiotic prescribing for adult Blue Cross Blue Shield of Michigan (BCBSM) members. (The project is a non-profit partnership between the University of Michigan and BCBSM.)
While antibiotic prescribing in adults decreased 9.3 percent from 2007 to 2009, it increased 4.5 percent for children during the same time period. The studies found significant differences in prescribing patterns between rural southeast Michigan and the rest of the state, particularly for children. Children in rural southeastern Michigan were prescribed an average of .93 antibiotics per year, while elsewhere children were prescribed an average of 1.0 per year.
“The continuing high rate of antibiotic use for viral infections in children and adults — particularly outside of southeast Michigan — is of great concern, as is the increase in the use of broad spectrum antibiotics in children,” said Marianne Udow-Phillips, CHRT’s director. “Using antibiotics when they are unnecessary — or treating simple infections with drugs that should be reserved for the most serious infections — are practices that contribute to antibiotic resistance, making future infections harder to treat.”
Nearly half (49.1 percent) of antibiotic prescriptions in the study population were for broad spectrum antibiotics in 2009, compared to the national rate of 47 percent. Between 2007 and 2009, prescriptions for what the National Committee for Quality Assurance calls “antibiotics of concern” declined slightly in adults, decreasing 0.4 percent during that time period. In the same time period, antibiotics of concern prescribed to children increased 3.4 percent, from 44.9 percent to 46.4 percent.
One possible explanation for the rising rate in children is a rise in resistant pathogens in ear infections, according to the study brief. Other possible reasons are that kids get different infections than adults, and that some drugs that are used in adults are not used for pediatric patients. Read more »
*This blog post was originally published at ACP Internist*
March 2nd, 2011 by Jon LaPook, M.D. in News, Research, Video
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A new study finds that half of men in America are infected with the HPV virus. Dr. Jon LaPook reports on the growing concern that the virus in men could be responsible for an increase in head and neck cancers.
HPV Affects Half Of U.S. Men
A study out [yesterday] in The Lancet by Moffitt Cancer Center researcher Anna Giuliano, Ph.D., and her colleagues finds that 50 percent of men ages 18 to 70 in Brazil, Mexico, and the U.S. have genital infection with human papillomavirus (HPV). HPV is the virus that causes cervical cancer in women. It also causes warts and cancer of the genitals and anus in both men and women. Over the past several years, researchers have realized that the virus can also cause cancer of the head and neck.
Aimee R. Kreimer, Ph.D., of the National Cancer Institute, estimates that about 65 percent of the approximately 8,000 cancers of the tonsils and base of the tongue (oropharynx) seen in the U.S. in 2010 were from HPV infection; eighty percent of these are in men. The rates for HPV-associated cancers like these are increasing; for sites like the mouth and larynx that are associated with tobacco and alcohol use, the rates are decreasing (though still too high since too many people still smoke and abuse alcohol).
An infection rate of 50 percent for a virus that can cause cancer sounds scary. But knowing a few more facts about HPV helps put the risk in perspective. About 90 percent of men and women infected with HPV virus get rid of it on their own within about two years. There are many different strains of HPV — some that cause cancer and some that don’t. Only about 6 percent of men have genital infection with HPV 16 — the strain linked to more than 90 percent of cancers of the head and neck. And only about 0.6 percent of men have HPV 16 in specimens taken from their mouths; what percentage of those men go on to develop head and neck cancer is unknown. Read more »
