Propecia and Proscar are formulations of the drug finasteride. These medications are used to treat male pattern baldness and prostatic hypertrophy. Prior studies have found side effects including sexual changes (loss in libido and function) and now new studies are finding increased incidence of male breast cancer in some of the patients taking the drugs.
Health Canada has issued a warning:
Although the apparent risks are low, Health Canada issued a warning Thursday telling consumers the drug, finasteride, could be potentially dangerous. The drug, which comes in one-milligram and five-milligram formats, is used in the lower dose to treat baldness and the higher dose to treat non-cancerous enlarged prostate. Previous studies have raised flags about the five-milligram format, sold in Canada under the brand name Proscar, including an increased risk of prostate cancer.
As these drugs inhibit Read more »
*This blog post was originally published at Truth in Cosmetic Surgery*
Most medical centers routinely perform or require that breast tissue be sent to pathology for histologic examination. The authors of the article (referenced below) question whether this is useful when the breast tissue excised comes from an adolescent male with gynecomastia considering the benign nature of the condition.
Furthermore, the authors point out male breast cancer is rare and when it does occur it is most often in older males, not adolescent males:
In 2009, there were an estimated 1,910 new cases and 440 deaths related to male breast cancer, accounting for just 0.25% and 0.15% of all new cases of cancer and cancer deaths for males in the entire United States, respectively, with historical cohorts demonstrating that the peak incidence of male breast cancer occurs at approximately 71 years of age. More significantly, breast cancer becomes increasingly uncommon among younger age groups.
To look at the issue, the authors did a retrospective chart review of their patients younger than 21 years of age who had undergone subcutaneous mastectomy for gynecomastia between 1999 and 2010. A review of the literature was done, as was an informal survey of major children’s hospitals regarding their practice of histologic examination for adolescent gynecomastia. Read more »
*This blog post was originally published at Suture for a Living*