September 20th, 2011 by RyanDuBosar in Research
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Scientists have added a new species to the menagerie of animals that glow, after introducing jellyfish genes into cats that can now glow green.
Scientists report that they transferred genes from monkeys (and jellyfish) into cats in order to study feline immunodeficiency virus (FIV), the cat equivalent of HIV. In cats and in people, immunodeficiency viruses deplete infection-fighting T-cells. Key proteins called restriction factors that would normally defend against the viruses are ineffective. The research appears in the September issue of Nature Methods.
To research potential treatments, physicians, virologists, veterinarians and gene therapy researchers from the Mayo Clinic and in Japan sought to mimic the way evolution would generate protective protein versions, according to a Mayo Clinic press release. They inserted monkey versions of a gene into the cat genome using gamete-targeted lentiviral transgenesis. This is done by inserting genes into feline eggs before sperm fertilization.
The monkey restriction factor, TRIMCyp, blocks FIV by attacking and disabling the virus as it tries to invade a cell. In the lab, the transgenic cat lymphocytes resisted FIV replication. The scientists said that they can now test the potential of various restriction factors for Read more »
*This blog post was originally published at ACP Internist*
September 19th, 2011 by Stanley Feld, M.D. in Health Policy, Opinion
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As we get closer to January 2012, the originally scheduled implementation date for Accountable Care Organizations (ACOs), the time has come to reexamine the showpiece of President Obama’s Patient Protection and Affordable Care Act (PPACA) of 2010.
The final rules for ACO’s are now scheduled for release on January 2012. The implementation was originally scheduled for January 2012. As the original rules are being studied and interpreted the program for ACOs implementation became more confusing. Dr. Don Berwick (CMS Director) has refused to discuss the final rules until they have been published in the Federal Register.
“The ACO program is based on the hubristic assumption that the federal government can design the best organizational structure for the delivery of care, foster its development, and control its operation for the entire country.
The federal government has big-footed health system reform. Although there is no one right way to organize care, the federal government (Dr. Don Berwick and President Obama) thinks it has found one—and exerts top-down, bureaucratic control through PPACA to implement it.”
ACOs are supposed to be organizations that improve coordinated care. If an ACO decreases the cost of care Read more »
*This blog post was originally published at Repairing the Healthcare System*
August 29th, 2011 by Berci in News
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I’ve always been a great fan of what Mayo Clinic has been doing on social media. Then after Mayo Clinic Center for Social Media was launched, I became a member of the international external advisory board which I’m very proud of. I reported when they launched a patient community and also discussed how well they did this. Now the Center is 1 year old and still performs perfectly. An excerpt form their previous entry:
Here’s a sneak peek of a few topics that were discussed during Mayo’s retreat: Read more »
*This blog post was originally published at ScienceRoll*
July 29th, 2011 by Davis Liu, M.D. in Opinion
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Let me say first that I am a practicing primary care doctor who is very much focused on patient centered care. Though I cannot go back to being a patient who is unaware about what a doctor does, the terminology she uses, or what the importance of certain test results are, I can empathize with the overwhelming amounts of information, challenges, and stressors patients and families can have in navigating the healthcare system to get the right care. This is the reason I wrote my book.
However, over the past few months I’ve noticed a particularly disturbing trend. Patients are not consulting doctors for advice, but rather demanding testing for diagnoses which are not even remote possibilities. A little knowledge can be dangerous particularly in the context of little to no clinical experience. Where many patients are today are where medical students are at the end of their second year – lots of book knowledge but little to no real world experience.
More patients are becoming the day traders of the dot.com boom. Everyone has Read more »
*This blog post was originally published at Saving Money and Surviving the Healthcare Crisis*
July 22nd, 2011 by BarbaraFicarraRN in Opinion
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Recently, I had the pleasure of being surrounded by brilliant health care thought leaders. First, I delivered a social media presentation at the Eyeforpharma conference. Secondly, I sat in the audience at the Social Communications and Health Care 2011 conference to listen to others present on social media, and participate in a round-table discussion on social media.
It’s clear from the personal discussion that followed with folks from the pharma industry, medical device companies, and hospitals, that they understand the need for social media (or social networking), but they are cautious to dive in.
A few concerns I’ve heard: “social media can be paralyzing,” “senior leadership in the pharma industry is looking for the FDA to make decisions because it’s such a highly regulated industry,” and “it’s still so new, what’s the ROI?” Concerns are real; however there will always be concerns and questions. Sometimes, the best approach is to just dive right in.
The brilliant reason to dive deep into the social media health space is Read more »
*This blog post was originally published at Health in 30*
