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High-Dose Flu Vaccine For Older Adults

Dr. Novella  has recently written about this year’s seasonal flu vaccine and Dr. Crislip has reviewed the evidence for flu vaccine efficacy. There’s one little wrinkle that they didn’t address — one that I’m more attuned to because I’m older than they are.

I got my Medicare card last summer, so I am now officially one of the “elderly.” A recent review by Goodwin et al. showed that the antibody response to flu vaccines is significantly lower in the elderly. They called for a more immunogenic vaccine formulation for that age group. My age group. One manufacturer has responded. Read more »

*This blog post was originally published at Science-Based Medicine*

Who Should Get A Flu Shot? You Should

It’s that time of year again. Children back at school. Football season is underway and baseball playoffs to start soon. The television networks are rolling out their new shows.

And it’s also time to think about getting flu shots. I just got mine today as I have done annually since going to medical school.

Compared to last year, there isn’t as much news about the flu or the flu vaccine. This year the Centers for Disease Control and Prevention (CDC) gives clear guidelines that everyone aged 6 months and older should get the influenza vaccine. 

This month the American Academy of Pediatrics recommends that all healthcare providers should be required to get the influenza vaccine.

And one fact that hasn’t gotten much attention is whether the 2009 H1N1 virus is included in the 2010-2011 vaccine: Is it? Yes, it is. This year’s vaccine will be as safe as vaccines in past years as the production process is unchanged. Inclusion of the 2009 H1N1 virus will not be a problem. Read more »

*This blog post was originally published at Saving Money and Surviving the Healthcare Crisis*

New Study: Shingles Vaccine Is Safe And Effective

Shingles (herpes zoster) is no fun. It usually begins with a couple of days of pain, then a painful rash breaks out and lasts a couple of weeks. The rash consists of blisters that eventually break open, crust over, and consolidate into an ugly plaque. It is localized to one side of the body and to a stripe of skin corresponding to the dermatomal distribution of a sensory nerve.

Very rarely a shingles infection can lead to pneumonia, hearing problems, blindness, brain inflammation (encephalitis) or death. More commonly, patients develop postherpetic neuralgia (PHN) in the area where the rash was. The overall incidence of PHN is 20%; after the age of 60 this rises to 40%, and after age 70 it rises to 50%. It can be excruciatingly painful, resistant to treatment, and can last for years or even a lifetime. Read more »

*This blog post was originally published at Science-Based Medicine*

The Return Of Mumps

I write this post with a great deal of trepidation. The last time I perused the Medical Voices website I found nine questions that needed answering. So I answered them. One of the consequences of that blog entry was the promise that Medical Voices was poised to “tear my arguments to shreds.” Tear to shreds! Such a painful metaphor.

They specified that the shred tearing would be accomplished during a live debate, rather than a written response. While Dr. Gorski gave excellent reasons why such a debate is counterproductive, I am disinclined for more practical reasons. I am a slow thinker and a lousy debater and have never, ever, won a debate at home. If I cannot win pitted against my wife, what chance would I have against the combined might of the doctors and scientists at Medical Voices? My fragile psyche could not withstand the onslaught.

Still, there is much iron pyrite to be mined at Medical Voices and it may provide me for at least a years worth of entries. Please forgive me if I seem nervous or distracted. I have a Sword of Damocles hanging over my head and it may fall at any time. My writings may, without warning, be torn to pieces by the razor sharp logical sword of Medical Voices. Or maybe not. It is my understanding that Medical Voices will only answer with a debate, so maybe I am safe from total ego destruction.

This month, as I perused Medical Voices, I found it difficult to choose an article. So much opportunity and I have limited time to write. I finally decided on Why the New Mumps Outbreak Puts You At Risk by Robert J. Rowen, M.D. Read more »

*This blog post was originally published at Science-Based Medicine*

Nanopatches: The Future Of Vaccine Delivery?

Professor Mark Kendall of the Australian Institute for Bioengineering and Nanotechnology and his team have been investigating a novel way to deliver vaccines.

Their method makes use of nanopatches, which are fingernail-sized dermal patches with microscopic projections on their surface that hand vaccine off directly to the antigen-presenting cells just below the surface of the skin.

The scientists’ recent work in mice has shown that an immune response equivalent to that achievable by needle and syringe can be reached using 100 times less vaccine. Not only does the nanopatch appear to be a more effective delivery method, it’s also cheaper to produce and doesn’t require refrigeration, adjuvants or multiple doses. Read more »

*This blog post was originally published at Medgadget*

Latest Interviews

IDEA Labs: Medical Students Take The Lead In Healthcare Innovation

It’s no secret that doctors are disappointed with the way that the U.S. healthcare system is evolving. Most feel helpless about improving their work conditions or solving technical problems in patient care. Fortunately one young medical student was undeterred by the mountain of disappointment carried by his senior clinician mentors…

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How To Be A Successful Patient: Young Doctors Offer Some Advice

I am proud to be a part of the American Resident Project an initiative that promotes the writing of medical students residents and new physicians as they explore ideas for transforming American health care delivery. I recently had the opportunity to interview three of the writing fellows about how to…

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Latest Book Reviews

Book Review: Is Empathy Learned By Faking It Till It’s Real?

I m often asked to do book reviews on my blog and I rarely agree to them. This is because it takes me a long time to read a book and then if I don t enjoy it I figure the author would rather me remain silent than publish my…

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The Spirit Of The Place: Samuel Shem’s New Book May Depress You

When I was in medical school I read Samuel Shem s House Of God as a right of passage. At the time I found it to be a cynical yet eerily accurate portrayal of the underbelly of academic medicine. I gained comfort from its gallows humor and it made me…

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Eat To Save Your Life: Another Half-True Diet Book

I am hesitant to review diet books because they are so often a tangled mess of fact and fiction. Teasing out their truth from falsehood is about as exhausting as delousing a long-haired elementary school student. However after being approached by the authors’ PR agency with the promise of a…

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