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Quitting Smoking? Your Nicotine receptors Take Over A Month To Normalize

Nicotine withdrawal symptoms typically peak in the first week of abstinence and return to normal at around 3-4 weeks. It has long been known that certain nicotinic receptors (particularly the beta-2 subtype) are closely involved in nicotine addiction, and that smokers have a larger number of nicotine receptors in their brains than non-smokers. When the smoker quits, this large number of vacant, unstimulated receptors is believed to be involved in the resulting craving and distressing withdrawal (irritability, restlessness, depression, anxiety, poor concentration etc).

Earlier this year, a study published by Drs Kelly Cosgrove, Julie Staley and colleagues at Yale University, provided evidence on the time course of normalization of these receptors after quitting smoking. Read more »

This post, Quitting Smoking? Your Nicotine receptors Take Over A Month To Normalize, was originally published on Healthine.com by Jonathan Foulds, Ph.D..

Classic Smoking Cessation Study Suggests You Can Save A Life For $2000

Every now and again I like to pick one of the classic research studies on smoking cessation in order to highlight some of the key findings. Today I’m going to focus on the part of the Lung Health Study.

The Lung Health Study is certainly one of the best smoking cessation studies ever carried out, partly because of the comprehensive nature of the assessment and follow-up of its 5,887 participants and partly because it was way ahead of its time in delivering a truly “state-of-the-art” intensive smoking cessation intervention which was compared in a randomized manner to the effects of “usual care”. The Lung Health Study (LHS) was a randomized clinical trial of smoking cessation and inhaled bronchodilator therapy in smokers 35 to 60 years of age who did not consider themselves ill but had evidence of mild to moderate airway obstruction. Read more »

This post, Classic Smoking Cessation Study Suggests You Can Save A Life For $2000, was originally published on Healthine.com by Jonathan Foulds, Ph.D..

Menthol: Mounting Evidence That It Makes Smoking Cessation More Difficult

I’m writing from the second conference on menthol and cigarettes, in Washington DC. This conference was organized to review the evidence on the effects of menthol in cigarettes and to discuss what further research is necessary and what actions should be taken.

To me, the presentations appeared to suggest that right now the evidence that menthol cigarettes are more harmful to health is weak. However, the evidence that menthol cigarettes are a starter product for youth and that menthol cigarettes can (under certain circumstances) be more addictive and harder to quit, is quite strong and getting stronger all the time. Read more »

This post, Menthol: Mounting Evidence That It Makes Smoking Cessation More Difficult, was originally published on Healthine.com by Jonathan Foulds, Ph.D..

Big Tobacco Now Marketing Fruit Flavored Cigars To Youth

Now that the U.S. Food and Drug Administration (FDA) has the power to regulate tobacco products we will see more meaningful moves to reduce the harmfulness and addictiveness of tobacco, as well as to reduce its addictiveness to young people. However, we should also expect the tobacco industry to respond by trying to find loopholes that help it get around these regulatory moves.

The first example is the ban on added flavors to cigarettes (which currently excludes menthol flavor, i.e. it is not banned automatically). Recently I’ve noticed an increased promotion of flavored cigars, often being sold as singles, in bright colorful packaging. The current FDA flavor regulation doesn’t ban fruit, candy and other flavors in cigars or smokeless tobacco, just cigarettes. Read more »

This post, Big Tobacco Now Marketing Fruit Flavored Cigars To Youth, was originally published on Healthine.com by Jonathan Foulds, Ph.D..

Smoking May Worsen Multiple Sclerosis

When thinking of the health risks of smoking, almost everyone is aware that smoking causes lung cancer and respiratory diseases. The connection between inhaling smoke into the lungs and developing diseases of the lung is immediately plausible. But every year medical researchers discover more and more diseases that are worsened by smoking.

One example that recently caught my attention is multiple sclerosis (MS). MS is a very serious neurological condition caused partly by damage to the myelin sheath covering cells and their connections in the central nervous system. The precise neurological symptoms the person experiences depends largely on which part of their central nervous system is affected. Read more »

This post, Smoking May Worsen Multiple Sclerosis, was originally published on Healthine.com by Jonathan Foulds, Ph.D..

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