August 29th, 2007 by Dr. Val Jones in Expert Interviews, News
Tags: Cancer, Cardiology, News, Pharmaceuticals, Research, Weight Loss
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We’ve known for quite a while that lowering your cholesterol can reduce your risk of heart disease, heart attack, and stroke. Low fat diets, weight loss, and exercise can help people to control their cholesterol levels – but for those who do not succeed with these methods, a class of medications have been developed (known as “statins”) to reduce cholesterol. These drugs have been so successful at reducing cholesterol that some doctors have joked about putting statins in the water supply. In fact, 36 million Americans take a statin every day, generating annual sales of
$15.5 billion for the manufacturers, and making two statins – Lipitor and
Zocor – the top two best-selling drugs in the USA.
Four new studies were published in the past week about these drugs. I thought I’d summarize the findings for you to keep you up to speed with the very latest statin information.
Statins May Reduce Mortality After Having A Stroke
Spanish researchers followed the progress of 89 stroke patients who were already taking statins. For the first three days after the stroke, 46 patients received no statins, and 43 got their normal dose. After three months, 27 people – 60 % of the “no statins”
group – had either died or were disabled to the point that they needed
help to live a normal life, compared with 16 people from the group
allowed to keep taking statins.
This small study suggests that stroke patients should not stop taking their statins. More research is needed to clarify the role of statins in stroke.
Statins May Reduce The Brain Plaques Associated With Alzheimer’s Disease
Researchers at the University of Washington examined the brain tissue of 110 people who had donated their brains to research upon their death. They found there were
significantly fewer plaques and tangles (the hallmarks of Alzheimer’s disease) in the brains of people who had taken statins compared with those who had not. This is good news, but will require further research to determine whether or not statins could be used (or should be used) specifically for the treatment or prevention of Alzheimer’s Disease.
Statins Don’t Seem To Reduce The Risk of Colon Cancer
A group of Greek researchers conducted a review of the scientific literature to see if there may be a reduction in colon cancer rates among people who take statins. They found no evidence that statins reduce the risk of colon cancer.
Statin Side Effects Appear To Be Ignored By Some Physicians
The journal Drug Safety surveyed 650 patients about their experience with statins. Eighty-seven percent of patients reportedly spoke to their physician
about the possible connection between statin use and a symptom.
Physicians were more
likely to deny than affirm the possibility of a connection. Rejection
of a possible connection was reported to occur even for symptoms with
strong literature support for a drug connection. This report is concerning since it seems to suggest that physicians don’t take patient complaints as seriously as they should.
I asked Dr. Frank Smart what he thought about the side effects of statins and whether or not physicians should be more aware of them.
“The statin side effects exist
but in my opinion are overplayed. In my practice about 5% of people on statins
have some muscle issues. Most improve with dose reduction or change to a more
hydrophyllic compound.
Physicians should be better educated about side effects and the one who
should do the educating is pharma, and websites like Revolution Health. Most docs are as
familiar with statin side effects as they are with other drug classes, so good
but not great. We would all love to raise the bar but it is tough as you
know.”
As many as 30% of patients reportedly experience a side effect from statins (including: headache, nausea,
vomiting, constipation, diarrhea, rash, weakness, and muscle pain) though severe muscle damage is very rare (for example, one article reported 24 cases in 252,460 patients.) Overall, statins have many health benefits and are well tolerated by the majority of patients.This post originally appeared on Dr. Val’s blog at RevolutionHealth.com.
August 23rd, 2007 by Dr. Val Jones in News
Tags: Animals, Infectious Disease, International, News
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I’ve always thought that bats got a bad rap. Just because one type of bat sucks blood from unsuspecting cattle, a whole vampire legend has unfolded, spun by Hollywood executives looking to feed upon a new movie blockbuster. But what about the other 700 species of bats who are vegetarian or eat mosquitoes and other bug pests?
Well, it’s getting harder and harder to defend these cuties, especially since two very incriminating reports were released recently. Apparently, rabid bats are turning up in Illinois, and certain fruit bats are carrying an ebola-like virus in Africa. So what’s a human to do? Basically, you should avoid bats – don’t touch them or play with them. And if you encounter one in your attic, it’s best to presume that it could carry the rabies virus and call in professionals to remove it. I would be especially wary of bats in sub-saharan Africa (for all those of you who frequent that part of the globe) since the Marburg virus they carry is quite lethal.
There have been recent cases of bat-bourn rabies in Canada so although it’s really rare – it’s something to keep in mind.
Here’s to bat free living…
Addendum: just today a woman in Chicago was bitten by a rabid bat when trying to remove it from her home. Guess she didn’t read my blog.
This post originally appeared on Dr. Val’s blog at RevolutionHealth.com.
August 20th, 2007 by Dr. Val Jones in News
Tags: Emergency Medicine, News, Obstetrics And Gynecology, Research
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There has been some recent buzz about the health risks of nail salon workers. Two studies suggest that constant exposure to nail product fumes might impact cognition in both nail salon workers and their unborn babies. Although the workers’ exposure is estimated at 1200 times that of the average American, it does make one wonder if any woman who frequents these places may be at some risk.
The first study involved neuropsychological testing of 33 female salon workers and comparing their results to 35 women matched controls. The researchers found that the salon workers did worse on tests of attention span and mental processing speed and their sense of smell was decreased. This study was too small and non-specific to tease out which chemicals might be the culprits, but the observations were concerning.
The second study involved cognitive testing of children born to 32 mothers who were exposed to organic solvents when they were in utero. Compared to a control group, the children (whose moms had been exposed to chemicals) performed more poorly on IQ tests and various other cognitive tests. Interestingly, the participants in this study were not nail salon workers – they held jobs ranging from funeral home embalming technicians to hair stylists, to dry cleaners.
The Environmental Protection Agency issued some guidelines for nail salons, and based on my experience I’d be surprised if salons adhere to even 1/3 of these guidelines on average. If you scroll to page 12 of the brochure, you’ll see that the EPA recommends wearing a “organic vapor cartridge respirator” which looks like something out of a HAZMAT video. I doubt that any nail salons provide these for their staff… and if they did, what would clients make of it?
And so I think these small studies raise an interesting question: how safe is it to be exposed to organic solvents at all? We need to do more research to tease out the exact risks of each individual chemical, and at which concentrations. As for me, I’d urge pregnant women to minimize their exposure wherever possible, and strongly consider avoiding salons that offer acrylic nail services. Until we know exactly how harmful these chemicals are – the best thing to do is to avoid them wherever possible. The potential for solvent-related cognitive decline is worrisome enough – but allergies and asthma exacerbations are far more common. For a full list of chemicals known to be harmful (and their side effects) please review the EPA brochure, pages 4-5.This post originally appeared on Dr. Val’s blog at RevolutionHealth.com.
August 19th, 2007 by Dr. Val Jones in News
Tags: Diabetes, Fraud, News
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Thanks to MedGadget for bringing this to my attention. Did you know that as many as 1 million fake diabetes test strips (manufactured in China but imported via Canada) made it onto the US market? About 10 million Americans use the One Touch Ultra system for measuring their glucose and titrating their insulin doses. Bloomberg news had this to say:
“Growth in counterfeit medicines and devices is probably
the biggest health threat besides infectious disease,” says
Peter Pitts, director of the Center for Medicines in the Public
Interest in New York and formerly an FDA official investigating
knockoff drugs.
The court filings disclose, for the first time, that China
is the source of about one million phony test strips that have
turned up in at least 35 states and in Canada, Greece, India,
Pakistan, the Philippines, Saudi Arabia, and Turkey.”
The test strips don’t measure glucose levels reliably and could result in patients dosing their insulin incorrectly. So be careful out there, folks… make sure that the test strips you use are not counterfeit. Check the lot number on your package to make sure it’s not one of these fake numbers.This post originally appeared on Dr. Val’s blog at RevolutionHealth.com.
August 14th, 2007 by Dr. Val Jones in News
Tags: Medical Training, Psychiatry
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A recent analysis (via KevinMD) of average IQs of individuals in certain professions revealed that doctors have a mean IQ of almost 10 points higher than lawyers. Go ahead and snicker, docs – we may be smarter, but are we more successful?
Social and economic success does not have a 1:1 correlation with IQ. The study authors list several other determinants of success:
Ambition, perseverance, responsibility, personal attractiveness, physical or artistic skills, access to social support and to favorable social and economic networks and resources.
So basically, you can be quite a dim wit – but with perseverance, artistic skills and personal attractiveness, the world is your oyster. Or better yet, you can have no redeeming qualities whatsoever, but be born into a favorable social and economic network and do just fine.
However, in medicine you’re not really going to get by on charm alone. The grueling nature of the educational process (and the vast amount of information that one must master) requires substantial cognitive reserves. So I’m not surprised that doctors do well on IQ tests. However, the sign of a great doctor is not his/her IQ, but a complex interplay of character, compassion, and emotional intelligence. That being said – if I’m wheeled into an ER after being run over by a truck, I’d be pretty glad to know that the man or woman taking care of me is smart. And you can be pretty sure that he/she will be.This post originally appeared on Dr. Val’s blog at RevolutionHealth.com.