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The Importance Of Increasing Our Knowledge Of Placebo Neurophysiology

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There has been an ongoing debate about placebos on SBM, both in the articles and in the comments. What does it mean that a treatment has been shown to be “no better than placebo?”  If our goal is for patients to feel better and they feel better with placebos, why not prescribe them? Do placebos actually do anything useful? What can science tell us about why a patient might report diminished pain after taking an inert sugar pill? The subject is complex and prone to misconceptions. A recent podcast interview offers a breakthrough in understanding.

On her Brain Science Podcast Dr. Ginger Campbell interviewed Dr. Fabrizio Benedetti, a physician and clinical neurophysiologist who is one of the world’s leading researchers on the neurobiology of placebos. A transcript of the interview [PDF] is available on her website for those who prefer reading to listening. The information Dr. Benedetti presents and the expanded remarks by Dr. Campbell after the interview go a long way towards explaining the placebo phenomenon and its consequences for clinical medicine. Dr. Campbell also includes a handy list of references. I’ll try to provide a summary of the main points, but I recommend reading or listening to the original.

A common misconception is that Read more »

*This blog post was originally published at Science-Based Medicine*

Dermatologists Relocate To The Sunniest Parts Of The U.S.

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Dermatologists spend their days telling patients to avoid the sun and their careers striving to practice in it. They’re leaving the Midwest and mountain states to practice in the southern and western U.S.

To evaluate the migration patterns of dermatologists from residency to clinical practice, researchers reviewed data from the American Academy of Dermatology’s membership database. They looked at 7,067 dermatology residents who completed training before 2005 and were actively practicing in 2009. Results appeared at the September issue of the Archives of Dermatology.

Most graduates from Middle Atlantic and Pacific census divisions relocated Read more »

*This blog post was originally published at ACP Internist*

Electronic Cigarettes May Help Smokers Quit, But Are They Safe?

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Kicking the cigarette habit is one of the best things that smokers can do for themselves. Nicotine replacement products, prescription medications, and counseling can all help. What about the newest tobacco substitute, the electronic cigarette? Despite the appeal of so-called e-cigarettes, we don’t know enough about their safety or effectiveness to give them the green light.

Electronic cigarettes come in a variety of shapes. Some look like cigarettes, pipes, or cigars, while others are disguised as pens or other more socially acceptable items. Whatever their shape, they all are built around a battery-operated heating element, a replaceable cartridge that contains nicotine and other chemicals, and an atomizer that converts the chemicals into an inhalable vapor.

A study published this spring in the American Journal of Preventive Medicine concluded that electronic cigarettes may help smokers quit. Whether they are a safe way to quit is another question—preliminary studies from the FDA, New Zealand, and Greece raise some concerns.

There are three reasons to worry about electronic cigarettes. First, Read more »

*This blog post was originally published at Harvard Health Blog*

MRIs Shown To Cause Feelings Of Dizziness

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Researchers at Johns Hopkins published a study that reports that MRI scans CAN cause feelings of dizziness induced by magnetic fields causing motion of the electrically charged fluid of the inner ear.

In both ears, there is a “gyroscope” called the labyrinth. Whenever the head turns or a force like gravity is exerted on this system, fluid moves within, which tells the brain that motion has occurred. It’s much like looking into a glass of water and based on the way the water tilts in the glass, you can guess which way motion is occurring.

In any case, the study Read more »

*This blog post was originally published at Fauquier ENT Blog*

Research Shows A Higher Risk Of Cardiovascular Disease In Childless Men

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Photo by Tracy DuBosar

Married men who have no children have a 17% higher risk of dying from cardiovascular disease after the age of 50 than men with two or more children. But whether that’s because of a physical cause, a sociological effect or self-selection (sick people may choose not to have kids) isn’t known.

To determine if the number of kids predicts cardiovascular death, researchers used data from the NIH-AARP Diet and Health Study of nearly 135,000 men ages 50 to 71 without prior cardiovascular disease who were followed-up for an average of 10 years. That study mailed 3.5 million questionnaires from 1995 through 1996 to AARP members living in California, Florida, Pennsylvania, New Jersey, North Carolina, and Louisiana or in Atlanta or Detroit. Nearly 586,000 people returned the questionnaire, which underwent follow-up surveys in 1996-1997 and 2004-2006. Results appeared online Sept. 26 in the journal Human reproduction.

Almost all (92%) men had Read more »

*This blog post was originally published at ACP Internist*

Latest Interviews

IDEA Labs: Medical Students Take The Lead In Healthcare Innovation

It’s no secret that doctors are disappointed with the way that the U.S. healthcare system is evolving. Most feel helpless about improving their work conditions or solving technical problems in patient care. Fortunately one young medical student was undeterred by the mountain of disappointment carried by his senior clinician mentors…

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How To Be A Successful Patient: Young Doctors Offer Some Advice

I am proud to be a part of the American Resident Project an initiative that promotes the writing of medical students residents and new physicians as they explore ideas for transforming American health care delivery. I recently had the opportunity to interview three of the writing fellows about how to…

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Latest Book Reviews

Book Review: Is Empathy Learned By Faking It Till It’s Real?

I m often asked to do book reviews on my blog and I rarely agree to them. This is because it takes me a long time to read a book and then if I don t enjoy it I figure the author would rather me remain silent than publish my…

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The Spirit Of The Place: Samuel Shem’s New Book May Depress You

When I was in medical school I read Samuel Shem s House Of God as a right of passage. At the time I found it to be a cynical yet eerily accurate portrayal of the underbelly of academic medicine. I gained comfort from its gallows humor and it made me…

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Eat To Save Your Life: Another Half-True Diet Book

I am hesitant to review diet books because they are so often a tangled mess of fact and fiction. Teasing out their truth from falsehood is about as exhausting as delousing a long-haired elementary school student. However after being approached by the authors’ PR agency with the promise of a…

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