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Drug Shown To Protect Obese Mice From The Diseases Of Obesity

I usually choose not to write about the “new new scientific thing” that gets picked up by the press,  because early research is usually not reproducible and good science takes a long time to validate as true.  But since we know that mice and rats that are kept on low-calorie diets live 30% longer (and healthier) than their fat cohorts, I was interested in a new research compound, SRT-1720,  that was shown to protect obese mice from diseases of obesity.  Fat mice lived 44% longer if they were given this drug.

The “designer” drug works by Read more »

*This blog post was originally published at EverythingHealth*

Reducing The Use Of CT Scans In Children

Well, this is satisfying. Over the years, in our ER we have mirrored the nationwide trend and have significantly increased the utilization of CT scans across the board. The reasons are manifold. Some cite malpractice risks, and indeed in our large group we have had one lawsuit for a pediatric head injury and another for a missed appendicitis which probably did contribute. But, in my opinion, there have been many other drivers of the increased use. For one, CTs have gotten way, way better over the last 15 years, which quite simply has made them a better diagnostic tool. They’ve also gotten way faster. As the facilities have invested in CT scanners, they have increased their capacity and increased their staffing, so the barriers to their use have rapidly diminished. I am so old that I remember when ordering a CT involved calling a radiologist and getting their approval! No more of that, I can tell you.

But a couple of years ago, we really started paying attention (perhaps belatedly) to Read more »

*This blog post was originally published at Movin' Meat*

Fab Antivenom Found To Cause Fewer Allergic Reactions Than Previously Thought

Crofab AntivenomThe current standard of care with regard to using antivenom for pit viper snakes (e.g., rattlesnakes, copperheads, cottonmouths) in North America is to use Crotalidae polyvalent immune Fab antivenom (CroFab;FabAV). This antivenom is created using a process that obtains antibodies “raised” by immunizing sheep and then harvesting and purifying the product. One of the major benefits of using this product is to take advantage of a lesser incidence of allergic reactions (than have traditionally been observed with previous products). It appears that the situation regarding the incidence of allergic reactions may be better than previously thought.

In the article, “Short Term Outcomes After Fab Antivenom Therapy for Severe Crotaline Snakebite,” Eric Lavonas, MD and colleagues (Ann Emerg Med 2011;57:128-137) examined Read more »

This post, Fab Antivenom Found To Cause Fewer Allergic Reactions Than Previously Thought, was originally published on Healthine.com by Paul Auerbach, M.D..

The Athletic Heart: How It Functions

It may seem a little formal to say this, but I would like to start by stating my goals for today’s post:

  • Introduce the concept of the athletic heart;
  • Touch upon the notion of sudden death of the athlete;
  • Explain what an ECG really is, and how it may help diagnose heart disease;
  • Review a recent study about the common ECG variant seen in athletes…Early repolarization.

Intro: The adaptations of the human heart never cease to amaze me. Physical training transforms our hearts into high performance engines. Repeated sessions of interval training, combined with longer aerobic efforts, and sprinkled with adequate rest maximize our ability to keep pressure on the pedals, or run the sixth mile of the 10k at the same pace as the first, or for you swimmers, to keep getting back to the wall on the 1:15 mark.

Fitness also brings measurable changes in things we can observe. Read more »

*This blog post was originally published at Dr John M*

CDC Outlines Injury Prevention Strategies In Extreme Weather Conditions

Photo: the sun.It may seem rather unusual to talk about injuries and weather in the same context, but extreme weather can pose significant risks for many kinds of injury.  Currently, many parts of the United States are experiencing a major heat wave, with record-setting heat and heat indices over the next few weeks.  As we have seen in the recent past, deaths are occurring from heat-related and possibly from participation in outside activities that increase the risk of heat-related illness.

During the month of August, many athletes train for the fall sports season, sometimes participating in two practices a day over the course of a few weeks.  While training is necessary and important for athletes to build up their stamina and to improve their performance, health consequences can be deadly if Read more »

*This blog post was originally published at CDC Injury Center: Director's View Blog*

Latest Interviews

IDEA Labs: Medical Students Take The Lead In Healthcare Innovation

It’s no secret that doctors are disappointed with the way that the U.S. healthcare system is evolving. Most feel helpless about improving their work conditions or solving technical problems in patient care. Fortunately one young medical student was undeterred by the mountain of disappointment carried by his senior clinician mentors…

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How To Be A Successful Patient: Young Doctors Offer Some Advice

I am proud to be a part of the American Resident Project an initiative that promotes the writing of medical students residents and new physicians as they explore ideas for transforming American health care delivery. I recently had the opportunity to interview three of the writing fellows about how to…

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Latest Book Reviews

Book Review: Is Empathy Learned By Faking It Till It’s Real?

I m often asked to do book reviews on my blog and I rarely agree to them. This is because it takes me a long time to read a book and then if I don t enjoy it I figure the author would rather me remain silent than publish my…

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The Spirit Of The Place: Samuel Shem’s New Book May Depress You

When I was in medical school I read Samuel Shem s House Of God as a right of passage. At the time I found it to be a cynical yet eerily accurate portrayal of the underbelly of academic medicine. I gained comfort from its gallows humor and it made me…

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Eat To Save Your Life: Another Half-True Diet Book

I am hesitant to review diet books because they are so often a tangled mess of fact and fiction. Teasing out their truth from falsehood is about as exhausting as delousing a long-haired elementary school student. However after being approached by the authors’ PR agency with the promise of a…

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