December 7th, 2011 by RyanDuBosar in News, Research
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Don’t assume elderly heart failure patients are assumed to prefer improved quality of life over longevity, study authors noted. The majority of them prefer longevity over quality of life, half expressed a desire for resuscitation if needed, and it was difficult to predict individual preferences.
Researchers looked at patients’ willingness to trade survival time for quality-of-life and the preferences for among 622 heart failure patients aged 60 or older participating in the Trial of Intensified vs. Standard Medical Therapy in Elderly Patients with Congestive Heart Failure.
End-of-life preferences were assessed by using a time trade-off tool and one question concerning CPR preference. To assess time trade-off, patients were asked whether they preferred living 2 years in their current state of health or living 1 year in excellent health. If 1 year in excellent health was chosen, the patients were asked whether they would prefer 2 years in their current state of health or 6 months in perfect health. If 2 years in the current state were chosen, then they were asked whether they would prefer 2 years in their current state of health or 18 months in perfect health. The series continued until the choices were the same. This time point subtracted from 24 months derived the number of months of survival time that the patient would be willing to trade.
End-of-life preferences were assessed at baseline, and at 12 and 18 months. Read more »
*This blog post was originally published at ACP Hospitalist*
December 6th, 2011 by Medgadget in Research
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Obesity is the most significant chronic healthcare crisis facing the United States, as well as other countries. Already 1 out of every 3 adults, and 1 out of every 6 children or adolescents, in the U.S. is obese! Leptin is a hormone that has received considerable attention since its discovery in 1994 for its role in regulating metabolism (like a thermostat, or adipostat) and implications for obesity. High leptin levels are associated with feeling satiated and an active metabolism. Though many overweight people have high levels of circulating leptin, it’s been found that their hypothalamic neurons do not receive the signal – a phenomenon known as “leptin resistance.” An animal model that mirrors this is db/db mice, which lack leptin receptors on the surface of they hypothalamic neurons and are therefore morbidly obese (see image).
Reporting in Science this past week, researchers at Harvard Medical School transplanted neurons with the leptin receptor into the hypothalami of db/db mice and as a result were able to partially restore leptin sensitivity and ameliorate their obesity. Two to three months after transplanting 15,000 (a relatively small number) fluorescently-tagged, leptin sensitive neurons into the db/db mice hypothalami, they observed statistically significant drops in blood sugar levels, leptin concentration, and fat mass. In terms of the mechanism and implications, the team concludes: Read more »
December 6th, 2011 by MellanieTrueHills in Research
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At the American Heart Association Scientific Sessions 2011, Dr. John Mandrola presented a poster on gender-specific results of atrial fibrillation ablation in a private practice setting. In this video interview with him about the poster, he mentioned that in his experience women appear to be more challenging to treat with atrial fibrillation ablation and do not appear to fare as well as men from it. In addition, it appeared that women were referred more often for AV node ablations than men.
*This blog post was originally published at Atrial Fibrillation Blog*
December 6th, 2011 by iMedicalApps in News
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A recent report by ABI Research, providing a broad overview of the mHealth industry, predicts extraordinary grown in health and fitness apps over the next five years.
The report, Mobile Devices and mHealth, includes forecasts for the next five years on factors such as regional smartphone adoption rates, app downloads, and wearable device usage among others. One major conclusion from the report is that the sports and health mobile application market will grow to over $400 million in 2016 – up from just $120 million in 2010.
Mobile health devices recently received a major boost with the incorporation of Bluetooth 4.0, which is expected to spur the development and launch of devices that will take advantage of the lower energy consumption. While much interest is focused on blood glucose monitors, remote monitoring of cardiac rhythms, and other similar parameters, one conclusion of this report is that some of the most impressive growth will be in health and fitness apps that are more directly consumer-oriented.
The report itself, for a rather hefty price, also addresses other questions like Read more »
*This blog post was originally published at iMedicalApps*
December 6th, 2011 by KerriSparling in True Stories
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Two weeks ago, I was in the emergency room for some severe stomach pain, down on the lower right hand side of my abdomen. After consulting with Dr. Google (bastard), I realized that it could be appendicitis. Knowing I was heading to Toronto the next afternoon, I didn’t want to take any chances with this pain. So I headed off to the ER to check things out.
Looooong story made Twitter-esque short, I didn’t have appendicitis. I just had some rogue stomach pain. However, while I was at the hospital, I asked to have my A1C run. I figured I was there, they were already drawing blood, so what’s one more vial?
“Can you guys grab an A1C while you’re at it?” I asked.
“Is your diabetes under control?” asked the doctor.
“Um … define control? I wear a pump, I wear a CGM, and I’m very aware of my disease. But I’ve been having a hard time juggling things lately, on just about every level, so I’m pretty sure my A1C is crap.”
The doctor shot me a very rude, very judgmental look. I shot one back at him.
“I’m asking you to run an A1C because I’m trying to regain control. I don’t have this nailed down and perfected, but I’m trying. Is that the wrong thing, in your opinion?” Read more »
*This blog post was originally published at Six Until Me.*
