November 27th, 2011 by Medgadget in Research
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Embryonic stem cells have the potential to treat a range of diseases and conditions for which current treatment options are lacking. Capable of differentiating practically into all of the types of tissues in the human body, the cells could be used in therapies to treat conditions such as paralysis, brain damage, and Parkinson’s disease. Among the many challenges to be overcome before human embryonic stem cells live up to their promise is difficulty in proving whether transplanted stem cells can integrate successfully in vivo.
Researchers from University of Wisconsin-Madison have announced progress on that front. Having created Read more »
*This blog post was originally published at Medgadget*
October 30th, 2011 by John Mandrola, M.D. in Research
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You don’t want this…
When it comes to the risk of stroke in atrial fibrillation, it pays to be a boy. Sorry, ladies.
An important question came up on my recent post on AF and stroke.
Why does being female give you an automatic point on CHADS2-VASc? I keep seeing it, but I don’t see why that is.
It doesn’t seem intuitive that female AF patients should have more strokes. Why? AF should equal AF.
But it does matter. When it comes to AF and stroke, women are very different.
Here are three references that support the fact that female gender increases the risk of stroke in AF.
–First: Read more »
*This blog post was originally published at Dr John M*
September 24th, 2010 by Dinah Miller, M.D. in Better Health Network, News, Opinion, Research
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In psychiatry, we’ve had a hard time drawing precise links between brain pathology and psychiatric disorders. We can do it for groups of people: “Disease X” is associated with changes in brain structure of “Brain Area Y” or metabolic changes in “Brain Area Z.” But it’s groups, not individuals, and it’s an association, not a cause-and-effect, or a definite. We still can’t use this information for diagnosis, and there are still patients with any given psychiatric diagnoses who will have brains where “Area Y” is the same size as those without the disorder. We’re learning.
From what I read in this New York Times article, Owen Thomas was a bright, talented young man with no history of psychiatric disorder and no history of known concussion. In April, he committed suicide — a tragedy beyond words.
Sometime people commit suicide and everyone is left to wonder: There was no depression, no obvious precipitant, no note left behind, and every one is left to wonder why. The guilt toll on the survivors is enormous, as is the grief for their families and communities. In this case, according to the Philadelphia Inquirer, the young man was apparently struggling with the stress of difficult school work and concerns about his team and employment.
Owen’s family donated his brain to Boston University’s Center for the Study of Traumatic Encephalopathy. They discovered that Owen’s brain showed damage similar to that seen in older NFL players — he had a condition called chronic traumatic encephalopathy. Read more »
*This blog post was originally published at Shrink Rap*
September 23rd, 2010 by Harriet Hall, M.D. in Better Health Network, Book Reviews, Opinion, Quackery Exposed, Research
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It infuriates me when someone misappropriates the word “science” to promote treatments that are not actually based on science. I have just read a book entitled The PTSD Breakthrough: The Revolutionary Science-Based Compass RESET Program by Dr. Frank Lawlis, a psychologist who is the chief content advisor for Dr Phil and The Doctors. There is very little science in the book and references are not provided. It amounts to an indiscriminate catalog of everything Dr. Lawlis can imagine that might help post-traumatic stress disorder (PTSD) patients.
He describes recent brain imaging studies suggesting that signs of traumatic brain injury are associated with PTSD. He thinks PTSD can no longer be considered a psychological condition, but must be approached as a complex biological, physical, psychological, and spiritual condition. He says many of these patients have brain damage. Read more »
*This blog post was originally published at Science-Based Medicine*
February 19th, 2010 by Medgadget in Better Health Network, News, Research
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Have Caltech scientists discovered an area of the brain evolved since the development of currency? The headline effectively suggests that, but the truth is probably a bit more nuanced.
The research team responsible for these findings consists of Benedetto de Martino, a Caltech visiting researcher from University College London and first author on the study, along with Caltech scientists Colin Camerer, the Robert Kirby Professor of Behavioral Economics, and Ralph Adolphs, the Bren Professor of Psychology and Neuroscience and professor of biology.
The study involved an examination of two patients whose amygdalae had been destroyed due to a very rare genetic disease; those patients, along with individuals without amygdala damage, volunteered to participate in a simple experimental economics task. Read more »
*This blog post was originally published at Medgadget*
