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Drug Shown To Protect Obese Mice From The Diseases Of Obesity
I usually choose not to write about the “new new scientific thing” that gets picked up by the press, because early research is usually not reproducible and good science takes a long time to validate as true. But since we know that mice and rats that are kept on low-calorie diets live 30% longer (and healthier) than their fat cohorts, I was interested in a new research compound, SRT-1720, that was shown to protect obese mice from diseases of obesity. Fat mice lived 44% longer if they were given this drug.
The “designer” drug works by Read more »
*This blog post was originally published at EverythingHealth*
Some Young Europeans Are Starting To Eat Like Americans
For years I have touted the health benefits of the “Mediterranean Diet” and encouraged patients to eat like the Europeans. Fresh farm vegetables, olive oil, fish and red wine have been linked with longevity and good health. I just read in NPR news that young Italians are forgoing the eating patterns of their elders and are imitating the “U.S. diet”. The result is soaring obesity, just like in the United States.
According the the article, young Italians ages 6-12 are sitting in front of the TV and are eating fast foods and soda. In just three generations, the eating habits and activity of kids has changed from their healthy grandparents. Italian health officials say obesity is reaching epidemic proportions.
Part of the diet changes are a result of Read more »
*This blog post was originally published at EverythingHealth*
Why Is Weight Gain Contagious? Monkey See, Monkey Do
One of the big health news stories of 2007 was a study showing that your friends influence the size of your waist (and the rest of your body). Like any study, it raised as many questions as it answered, including why this happens. A new study from Arizona State University looked into that question by testing three pathways by which friends might influence one another’s body size:
- Collaboration. Over time, you might start to share the ideas of the people close to you after talking with them about what the proper body size is. Then you might choose your food and exercise habits in order to reach that body size, whether that means eating more food to look like your plus-sized friends, or less food to look like your thin ones.
- Peer pressure. You feel bullied into trying to look like your friends and family members. They make you feel bad about your body, so you go about eating and exercising to look like them.
- Monkey see, monkey do. You change your habits to mirror those of your friends without necessarily thinking or talking about an ideal body weight. Alexandra Brewis Slade, PhD, one of the Arizona State researchers, gave an example of this pathway that most of us can relate to: You’re at a restaurant with friends and the waiter brings over the dessert menu. Everyone else decides not to order anything, so you pass, too, even though you were dying for a piece of chocolate mousse cake.
All three of these pathways are based on the idea that loved ones share social norms, the implicit cultural beliefs that make some things okay, others not. Read more »
*This blog post was originally published at Harvard Health Blog*
Obesity Beats Adiposity For Cardiovascular Risk
Obesity contributes to cardiovascular risk no matter where a person carries the weight, concluded researchers after looking at outcomes for nearly a quarter-million people worldwide.
Body mass index, (BMI) waist circumference, and waist-to-hip ratio do not predict cardiovascular disease risk any better when physicians recorded systolic blood pressure, history of diabetes and cholesterol levels, researchers reported in The Lancet.
The research group used individual records from 58 prospective studies with at least one year of follow up. In each study, participants were not selected on the basis of having previous vascular disease. Each study provided baseline for weight, height, and waist and hip circumference. Cause-specific mortality or vascular morbidity were recorded according to well defined criteria.
Individual records included 221,934 people in 17 countries. In people with BMI of 20 kg/m2 or higher, hazard ratios for cardiovascular disease were 1.23 (95 percent CI, 1.17 to 1.29) with BMI, 1.27 (95 percent CI, 1.20 to 1.33) with waist circumference, and 1.25 (95 percent CI, 1.19 to 1.31) with waist-to-hip ratio, after adjustment for age, sex, and smoking status. After adjusting for baseline systolic blood pressure, history of diabetes, and total and HDL cholesterol, corresponding hazard rations were 1.07 (95 percent CI, 1.03 to 1.11) with BMI, 1.10 (95 percent CI, 1.05 to 1.14) with waist circumference, and 1.12 (95 percent CI, 1.08 to 1.15) with waist-to-hip ratio.
BMI, waist circumference, or waist-to-hip ratio did not importantly improve risk discrimination or predicted 10-year risk, and the findings remained the same when adiposity — the carrying of adipose tissue (fat) — measures were considered. Read more »
*This blog post was originally published at ACP Internist*
