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Actual Living, Breathing Lungs On Stage At TEDMED 2010

Dr. Shaf Keshavjee, a thoracic surgeon and director of the Toronto Lung Transplant Program, showed the amazing miracle of modern lung transplantation at TEDMED 2010. Here’s his fascinating talk where an actual living, breathing set of porcine lungs were brought on stage for hands-on inspection by the audience:

Here’s a quick interview we were able to get with Dr. Keshavjee just after the talk: Read more »

*This blog post was originally published at Medgadget*

Combating Concussions: Impact Sensors For NFL Players’ Helmets

Anyone who’s ever watched football, the American variety, knows how rough of a sport it can be. With 22 fast-moving players (some weighing as much as 350 pounds) scrambling and tackling for possession of the pigskin, injuries are inevitable.

One of the scariest injuries a football player can get is a concussion. With its commonly insidious onset, concussions of the brain are often difficult to diagnose, or immediately treat to avoid long-term consequences.

The National Football League (NFL) has announced that they will be launching a pilot program next season in which accelerometers will be placed in players’ mouthpieces, earpieces, and helmets to analyze how blows to the head relate to the effects and severity of concussions and other traumatic brain injuries. The data could potentially help team doctors diagnose the severity of a concussion within a few minutes. Collected long-term from groups of players, the impact data could help coaches and doctors determine how players get injured and the possible effects of such injuries. Such data could also help engineers design a better football helmet.

As long as the game of football continues to be played, concussions will be pretty much impossible to avoid. However, changing technology and increasing knowledge of traumatic brain injury will hopefully only make football a safer, more enjoyable sport.

Wired article: Impact Sensors Slated for NFL Helmets Next Season…

Medgadget archive: Football helmet technology…

*This blog post was originally published at Medgadget*

Personal Genetic Testing: Psychological And Behavioral Effects

Genome-wide profiling is increasingly being marketed towards consumers to assess their risk of developing certain diseases. However, there has been little research into the psychological effects of these tests.

Researchers from Scripps Translational Science Institute have now looked into these effects in a large group of patients. They followed 2,037 participants who took the Navigenics Health Compass, a test that assesses the risk for about 20 common diseases, for a period of three months.

Taking the test did not increase anxiety symptoms, dietary fat intake, or exercise behavior. There was some test-related distress correlated with the average estimated lifetime risk of getting the diseases tested for, but at the same time 90.3 percent of all subjects had no test-related distress at all. The use of screening tests did not change among the group and notably health effects of the test were not studied.

In conclusion, personal genetic testing does not seem to generate a lot of distress, although the study was clearly limited by a high dropout percentage of 44 percent and the self-selection of participants who opted to do the test.

Article in New England Journal of Medicine: Effect of Direct-to-Consumer Genomewide Profiling to Assess Disease Risk

Flashback: An Interview with Navigenics…

*This blog post was originally published at Medgadget*

Kids With Dyslexia: Predicting Their Reading Skills With MRI

An international team of researchers has developed a rather reliable test that predicts the future improvement of reading abilities in kids with dyslexia. The method uses functional MRI (fMRI) and diffusion tensor magnetic resonance imaging (DTI) to scan the brain, and data crunching software to interpret the data. The researchers hope that the finding will help parents and therapists uniquely identify which learning tools are best for each child.

From the announcement by Vanderbilt University :

The 45 children who took part in the study ranged in age from 11 to 14 years old. Each child first took a battery of tests to determine their reading abilities. Based on these tests, the researchers classified 25 children as having dyslexia, which means that they exhibited significant difficulty learning to read despite having typical intelligence, vision and hearing and access to typical reading instruction.

During the fMRI scan, the youths were shown pairs of printed words and asked to identify pairs that rhymed, even though they might be spelled differently. The researchers investigated activity patterns in a brain area on the right side of the head, near the temple, known as the right inferior frontal gyrus, noting that some of the children with dyslexia activated this area much more than others. DTI scans of these same children revealed stronger connections in the right superior longitudinal fasciculus, a network of brain fibers linking the front and rear of brain. Read more »

*This blog post was originally published at Medgadget*

Glaucoma Testing Through The Eyelid

f34gdfg.jpgIntraocular pressure is usually measured by applying a force on the cornea using a tonometer. Although sufficiently accurate, tonometers are only used in ophthalmologist offices and so don’t measure intra-day pressures. They also fail with people post cataract surgery that have a thicker cornea. Researchers at University of Arizona have developed a new device that measures intraocular pressure through the eyelid.

From the University of Arizona College of Engineering:

The self-test instrument has been designed in Eniko Enikov’s lab at the UA College of Engineering. Gone are the eye drops and need for a sterilized sensor. In their place is an easy-to-use probe that gently rubs the eyelid and can be used at home.

“You simply close your eye and rub the eyelid like you might casually rub your eye,” said Enikov, a professor of aerospace and mechanical engineering. “The instrument detects the stiffness and, therefore, infers the intraocular pressure.” Enikov also heads the Advanced Micro and Nanosystems Laboratory.

While the probe is simple to use, the technology behind it is complex, involving a system of micro-force sensors, specially designed microchips, and math-based procedures programmed into its memory.

Link: New Glaucoma Test Allows Earlier, More Accurate Detection…

*This blog post was originally published at Medgadget*

Latest Interviews

IDEA Labs: Medical Students Take The Lead In Healthcare Innovation

It’s no secret that doctors are disappointed with the way that the U.S. healthcare system is evolving. Most feel helpless about improving their work conditions or solving technical problems in patient care. Fortunately one young medical student was undeterred by the mountain of disappointment carried by his senior clinician mentors…

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How To Be A Successful Patient: Young Doctors Offer Some Advice

I am proud to be a part of the American Resident Project an initiative that promotes the writing of medical students residents and new physicians as they explore ideas for transforming American health care delivery. I recently had the opportunity to interview three of the writing fellows about how to…

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Latest Book Reviews

Book Review: Is Empathy Learned By Faking It Till It’s Real?

I m often asked to do book reviews on my blog and I rarely agree to them. This is because it takes me a long time to read a book and then if I don t enjoy it I figure the author would rather me remain silent than publish my…

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The Spirit Of The Place: Samuel Shem’s New Book May Depress You

When I was in medical school I read Samuel Shem s House Of God as a right of passage. At the time I found it to be a cynical yet eerily accurate portrayal of the underbelly of academic medicine. I gained comfort from its gallows humor and it made me…

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Eat To Save Your Life: Another Half-True Diet Book

I am hesitant to review diet books because they are so often a tangled mess of fact and fiction. Teasing out their truth from falsehood is about as exhausting as delousing a long-haired elementary school student. However after being approached by the authors’ PR agency with the promise of a…

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