November 9th, 2011 by RyanDuBosar in Research
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Fear of the “freshman 15” weight gain is overrated, says one researcher who found that the average college student packs on only between about 2.5 and 3.5 pounds.
And it might not even be the college lifestyle that causes one’s backpack to become a little more snug. Rather, it’s part of the natural transition into adulthood. The typical freshman only gains about a half-pound more than a same-age person who didn’t go to college.
“Not only is there not a ‘freshman 15,’ there doesn’t appear to be even a ‘college 15’ for most students,” researchers said in a press release.
The researchers concluded that the myth of the freshman 15 may contribute to Read more »
*This blog post was originally published at ACP Internist*
January 26th, 2011 by Mark Crislip, M.D. in Opinion, Research
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It always somewhat surprises me how some interventions never seem to die. One therapy that refuses to be put to rest, or even to be clarified, is the use of cranberry juice for urinary tract infections (UTIs). PubMed references go back to 1962, and there are over 100 references. Firm conclusions are still lacking.
There is a reasonable, but incomplete, basic science behind the use of the cranberry juice for UTIs. E. coli , the most common cause of UTIs, causes infection in the bladder by binding to the uroepithelial cells. To do this, they make fimbriae, proteinaceous fibers on the bacterial cell wall. Fimbriae are adhesins that attach to specific sugar based receptors on uroepithelial cells. Think Velcro. Being able to stick to cells is an important virulence factor for bacteria, but not a critical one — it is not the sine qua non of bladder infections.
Are all E. coli causing UTIs fimbriated? No. It is the minority of E. coli that cause UTI that have fimbria, and the presence of fimbriae may be more important for the development of pyelonephritis (kidney infection) than cystitis (bladder infection). Read more »
*This blog post was originally published at Science-Based Medicine*
