March 8th, 2011 by Medgadget in Better Health Network, Research
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Duke University scientists have been successfully testing a new laser system they developed to identify cancerous skin moles. Two lasers in the system are used to identify the presence of eumelanin in biopsy slices and a future version of the device may work directly without having to sample the mole. According to an article in Science Translational Medicine, “the ratio of eumelanin to pheomelanin captured all investigated melanomas but excluded three-quarters of dysplastic nevi and all benign dermal nevi.” From the press release:
The tool probes skin cells using two lasers to pump small amounts of energy, less than that of a laser pointer, into a suspicious mole. Scientists analyze the way the energy redistributes in the skin cells to pinpoint the microscopic locations of different skin pigments.
The Duke team imaged 42 skin slices with the new tool. The images show that melanomas tend to have more eumelanin, a kind of skin pigment, than healthy tissue. Using the amount of eumelanin as a diagnostic criterion, the team used the tool to correctly identify all eleven melanoma samples in the study.
The technique will be further tested using thousands of archived skin slices. Studying old samples will verify whether the new technique can identify changes in moles that eventually did become cancerous.
Malignant melanoma under the new laser light. Clear deposits of eumelanin (red) appear in unhealthy tissue.
Press release: Lasers ID Deadly Skin Cancer Better than Doctors …
Abstract in Science Translational Medicine: Pump-Probe Imaging Differentiates Melanoma from Melanocytic Nevi
Flashback: Diagnosing Skin Cancers with Light, Not Scalpels
*This blog post was originally published at Medgadget*
August 31st, 2010 by Jeffrey Benabio, M.D. in Better Health Network, Health Tips
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Having a high-quality doctor’s visit takes effort on your doctor’s and yours. Here are 10 tips to get the most out of your next visit with a dermatologist:
1. Write down all the questions you have and things you want to discuss with me. Be sure to list any spots you’d like me to check or any moles that have changed. Have a loved one lightly mark spots on your skin they are concerned about.
2. Know your family history: Has anyone in your family had skin cancer? What type? Patients often have no idea if their parents have had melanoma. It matters. If possible, ask before seeing me.
3. Know your history well: Have you had skin cancer? What type? If you have had melanoma, then bring the detailed information about your cancer. Your prognosis depends on how serious the melanoma was, that is its stage, 1-4. You need to know how it was treated, if it had spread, and how deep it was. The answers to these questions determines the risk of your melanoma returning. Read more »
*This blog post was originally published at The Dermatology Blog*
July 13th, 2010 by Medgadget in Better Health Network, News, Research
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Yanko, the design blog we highlight occasionally, shows us a device design by Antonia Haaf meant to automatically detect melanoma, called Black Skin Cancer.
Details are vague, as they usually are with concept designs, but the device is meant to be placed over a suspected legion and “[analyze] 2D and 3D characteristics from melanocytic lesions with just one shot. Using a secret algorithm, the device recognizes critical lesions such as the nodular melanome.”
While pretty, commenter Widepers on the site points out: “Frankly, a magnifying glass and the skin doctor’s email might do the trick just as well.”
Yanko Designs: Detector VS Black Skin Cancer
*This blog post was originally published at Medgadget*
March 30th, 2010 by RamonaBatesMD in Better Health Network, Health Tips, News, Research
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The entire March issue of Archives of Dermatology appears to be dedicated to skin cancer — melanoma and non-melanoma.
Basal cell carcinoma (BCC) represents 65% to 75% of all skin cancers. Most occur on sun-exposed parts of the face, ears, scalp, shoulders, and back. Intense short-term UVB exposure is important in the formation of BCC. Clinical features include pearly translucent flesh-colored papules or nodules with superficial telangiectasias (broken blood vessels). More active lesions may have rolled edges or ulcerated centers.
Squamous cell carcinoma (SCC) represent 30% to 65% of all cutaneous malignancies. SCCs are most attributable to UVB exposure, long-term or accumulative exposure over years. Clinical features include crusted papules and plaques that may become indurated, nodular, or ulcerated. SCC may arise in chronic wounds, scars, and leg ulcers. Recurrent SCC development within 3 years is 18%, a 10-fold higher incidence compared with initial SCC diagnosis in the general population.
Malignant melanoma (MM) represents the most serious of all cutaneous malignancies. It is estimated that approximately 65% to 90% are caused by UV exposure, predominantly UVA. Roughly 10% of all melanoma cases are strictly hereditary. Read more »
*This blog post was originally published at Suture for a Living*
January 12th, 2010 by RamonaBatesMD in Better Health Network, Book Reviews, Health Tips
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Earlier today I wrote a short article which resulted in correspondence with one of the authors of the new book, ‘FDR’s Deadly Secret’ by Steven Lomazow and Eric Fettmann.
Dr. Steven Lomazow sent me a copy of his Archives of Dermatology article with Dr. Bernard Ackerman, this photo, and a pdf of his book which I have spent the afternoon reading.
The article goes through a series of photos of FDR from his younger days to his older ones, showing the progression and changes. From the article: Read more »
*This blog post was originally published at Suture for a Living*
