August 29th, 2011 by Harriet Hall, M.D. in Opinion, Research
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During the early days of the 2009 H1N1 influenza A pandemic, the popular herbal formula maxingshigan–yinqiaosan was used widely by TCM practitioners to reduce symptoms. (It’s hard to pronounce and spell, so I’ll refer to it as M-Y.) A new study was done to test whether M-Y worked and to compare it to the prescription drug oseltamivir. It showed that M-Y did not work for the purpose it was being used for: it did not reduce symptoms, although it did reduce the duration of one sign, fever, allowing researchers to claim they had proved that it works as well as oseltamivir.
“Oseltamivir Compared With the Chinese Traditional Therapy: Maxingshigan–Yinqiaosan in the Treatment of H1N1 Influenza” by Wang et al. was published in the Annals of Internal Medicine earlier this month. The study was done in China, which is notorious for only publishing positive studies. Even if it were an impeccable study, we would have to wonder if other studies with unfavorable results had been “file-drawered.” It’s not impeccable; it’s seriously peccable.
It was randomized, prospective, and controlled; but not placebo controlled, because they couldn’t figure out how to prepare an adequate placebo control. They considered that including Read more »
*This blog post was originally published at Science-Based Medicine*
August 27th, 2011 by RyanDuBosar in Research
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Heart attack patients are now being treated on average 32 minutes faster than they were five years ago, and medical societies are touting it as evidence of the success of national campaigns to treat heart attacks more quickly.
The study, “Improvements in Door-to-Balloon Time in the United States: 2005-2010,” found that the average time from hospital arrival to treatment declined from 96 minutes in 2005 to just 64 minutes in 2010. In addition, more than 90% of heart attack patients who required emergency angioplasty in 2010 received treatment within the recommended 90 minutes, up from 44% in 2005.
Also, the study reported that Read more »
*This blog post was originally published at ACP Hospitalist*
August 26th, 2011 by RyanDuBosar in Research
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Women gain weight after marriage and men after divorce, especially among those over 30, likely the result of “weight shock” to people’s routines in physical activity and diet, sociologists reported.
The research, led by a sociology doctoral student at The Ohio State University, was presented at a roundtable on Marriage and Family at the annual meeting of the American Sociological Association. They used data from the National Longitudinal Survey of Youth ’79, a nationally representative sample of men and women ages 14 to 22 in 1979. The same people were surveyed every year up to 1994 and every other year since then, reported a press release.
Data on more than 10,000 people surveyed from 1986 to 2008 was used to determine Read more »
*This blog post was originally published at ACP Internist*
August 26th, 2011 by Jessie Gruman, Ph.D. in Research
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Do you suffer from decision fatigue when you are sick or anxious or overwhelmed by bad health news? Does your doctor make less well-reasoned decisions about the 10th patient she sees before lunch? How about the surgeon during his second operation of the day? How about the radiologist reading the last mammogram in a daily batch of 60?
A provocative article by John Tierney in Sunday’s NYTimes Magazine adds a new layer of complexity to the body of knowledge collecting around decision-making processes. Considerable news reporting has focused on how cognitive biases influence our judgment and how many of us experience the abundance of choices available to us as a burden rather than a privilege. This article adds to that understanding: Our decision-making abilities appear to be powerfully affected by the demands of repeated decision making as they interact with depleted blood glucose levels. That fatigue mounts over a day of making decisions and as blood glucose levels fall between meals. In response, we tend to either make increasingly impulsive decisions without considering the consequences or to make no decisions at all. Tierney describes a study analyzing 1,100 parole decisions by judges over the course of a year: “Prisoners who appeared early in the morning received parole about 70 percent of the time, while those who appeared late in the day were paroled less than 10 percent of the time.”
The effects reported in the article were Read more »
*This blog post was originally published at Prepared Patient Forum: What It Takes Blog*
August 25th, 2011 by DrWes in Opinion, Research
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A new report published online in the Journal of the American College of Cardiology and reported in theHeart.org and elsewhere, suggests the infection rate of cardiac implantable electronic devices (CEID’s) between 1993 and 2008 has greatly increased from 1.53% in 2004 to 2.41% in 2008 (p < 0.001) with a dramatic rise in 2005:
Click image to enlarge
The authors explain this sudden increase on the basis of comorbities: Read more »
*This blog post was originally published at Dr. Wes*