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FDA Approves Tetanus/Diphtheria/Pertussis Vaccine For Adults Over 65

BoostrixMost of us are familiar with the need to achieve immunization against tetanus (“lockjaw”) and diphtheria. Fewer are familiar with the need to immunize against pertussis (“whooping cough”). Boostrix is a vaccine used to achieve immunity against all three. Until recently, there had not been a vaccine approved by the Food and Drug Administration (FDA) against pertussis intended for use in elders (ages 65 years and older). On July 8, 2011, the FDA approved Boostrix for use in this population of seniors.

The link to the FDA announcement is http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm262390.htm

Whooping cough is not a trivial disease. It is a highly communicable infectious disease caused by the bacterium Bordetella pertussis. It is transmitted by respiratory secretions or large droplets from the respiratory tract of an infected person. In children, whooping cough is typified by Read more »

This post, FDA Approves Tetanus/Diphtheria/Pertussis Vaccine For Adults Over 65, was originally published on Healthine.com by Paul Auerbach, M.D..

Article Recommends Herpes Zoster Vaccine For Adults Over 60

shingles.I am often asked by elder persons whether or not they should take the herpes zoster (“shingles”) vaccine. Up until this point, I have been answering “yes” based on my own experience, but now there is some data to support this recommendation.

In the article, “Herpes Zoster Vaccine in Older Adults and the Risk of Subsequent Herpes Zoster Disease,” Hung Fu Tseng and his colleagues reported their findings in the Journal of the American Medical Association (JAMA 2011;305[2]:160-161). They evaluated the risk of herpes zoster after persons received the vaccine in a general practice setting.

In a retrospective (looking back at a cohort of patients from medical records) study, the researchers compared Read more »

This post, Article Recommends Herpes Zoster Vaccine For Adults Over 60, was originally published on Healthine.com by Paul Auerbach, M.D..

Advancement In Research For A Safer Yellow Fever Vaccine

Paperwork proving administration of a yellow fever vaccine.Yellow fever is an affliction caused by a potentially lethal viral (flavivirus) hemorrhagic (causes bleeding) virus common in parts of Africa and South America. A highly effective vaccine made from live virus (known as the “17D vaccine”) is currently used to inject persons to prevent yellow fever; this vaccine is known to rarely cause serious adverse effects, namely, onset of allergic reactions, or a life-threatening or fatal infection that resembles yellow fever.

So, there is need for a safer (“nonreplicating”—in other words, not based on live virus) vaccine. In a recent article, “An Inactivated Cell-Culture Vaccine against Yellow Fever,” Thomas Monath, MD and his coauthors described their experience with a potentially safer vaccine (NEJM, 2011;364:1326-33). In their study, Read more »

This post, Advancement In Research For A Safer Yellow Fever Vaccine, was originally published on Healthine.com by Paul Auerbach, M.D..

Do You Know How To Recognize Deadly Bacterial Meningitis?

MenactraOne of the most feared infectious diseases for outdoor travelers—particularly children and young adults—meningitis caused by the bacterium Neisseria meningitidis (meningococcus). The infection can appear in outbreaks, most commonly abroad, particularly in sub-Saharan Africa and China.

The infection is spread in the respiratory secretions of humans. The disease appears in many forms, the most common of which are meningitis, pneumonia, and disseminated bacterial infection. The typical presentation of meningitis is fever, headache, and a stiff neck. If the cause is meningococcus, the victim may develop a skin rash, which consists of red dots or bumps, or a flat, more patchy dark red discoloration.

If the dark red dots begin to enlarge and coalesce into large purplish bruise-like discolorations, this is a bad sign. In the worst cases, a victim can develop shock, respiratory failure, diffuse bleeding, and death. Approximately one in 10 victims of meningococcal meningitis dies. Read more »

This post, Do You Know How To Recognize Deadly Bacterial Meningitis?, was originally published on Healthine.com by Paul Auerbach, M.D..

Vaccines: Top 10 Reasons To Get Your Shots

Vaccines have saved more lives than any other medical intervention in history. They are incredibly safe and effective and are well-tolerated by most people. In the US, the Centers For Disease Control and Prevention (CDC) carefully reviews all reports of adverse reactions that could be associated with vaccines. Over decades of review, they have found that the rate of potential severe reactions is so low that they cannot even calculate a risk.

There are many vaccines available for babies, children, and adults. Please check these vaccine schedules to make sure that you and your family are fully protected from vaccine-preventable diseases. (Or you can ask your doctor/nurse to review your vaccine needs with you in person.)

Vaccines for ages 0-6 click here.

Vaccines for ages 7-18 click here.

Vaccines for adults click here.

In case you have any doubts about the value of protecting yourself from disease, here are my top 10 reasons to get vaccinated: Read more »

Latest Interviews

IDEA Labs: Medical Students Take The Lead In Healthcare Innovation

It’s no secret that doctors are disappointed with the way that the U.S. healthcare system is evolving. Most feel helpless about improving their work conditions or solving technical problems in patient care. Fortunately one young medical student was undeterred by the mountain of disappointment carried by his senior clinician mentors…

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How To Be A Successful Patient: Young Doctors Offer Some Advice

I am proud to be a part of the American Resident Project an initiative that promotes the writing of medical students residents and new physicians as they explore ideas for transforming American health care delivery. I recently had the opportunity to interview three of the writing fellows about how to…

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Latest Book Reviews

Book Review: Is Empathy Learned By Faking It Till It’s Real?

I m often asked to do book reviews on my blog and I rarely agree to them. This is because it takes me a long time to read a book and then if I don t enjoy it I figure the author would rather me remain silent than publish my…

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The Spirit Of The Place: Samuel Shem’s New Book May Depress You

When I was in medical school I read Samuel Shem s House Of God as a right of passage. At the time I found it to be a cynical yet eerily accurate portrayal of the underbelly of academic medicine. I gained comfort from its gallows humor and it made me…

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Eat To Save Your Life: Another Half-True Diet Book

I am hesitant to review diet books because they are so often a tangled mess of fact and fiction. Teasing out their truth from falsehood is about as exhausting as delousing a long-haired elementary school student. However after being approached by the authors’ PR agency with the promise of a…

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