December 1st, 2011 by ErikDavis in Opinion, Research
Tags: Antioxidants, Beneficial, Detrimental, Diet and Nutrition, Effectiveness, Exercise, Folic Acid, Health, Multivitamins, Review, Skeptic, Supplements, Vitamins
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I have skeptical confession to make. I was once a panacea-seeking antioxidant-taker. As background, I’m a marathon runner and occasional triathlete. Several years ago, I was training for an Ironman triathlon, and banking 20+ hours of intense exercise per week. That may sound absurd to many (it does to me, now that I have kids) but that kind of training is necessary for the long races. So what did this pharmacist-wannabe-triathlete with access to discount vitamins do? He stocked up on the fancy bottles of multivitamins, the “endurance” version, of course — with extra antioxidants. Why did I supplement? I wanted to maximize my workouts, speed recovery, and minimize downtime and the risk of injury. Oxidation sounds bad — like a rusting car. Anti-oxidants sounded like the ultimate in preventative medicine. My workouts may have been more extreme, but the practice of supplementing if you exercise is common among athletes.
As it turns out, not only were the antioxidants likely ineffective, they may have compromised some of the gains I was seeking with all that training. That I didn’t evaluate the evidence at the time was my critical-thinking blind spot. Over the the past several years, more data on antioxidants and exercise have emerged. A recent review article, Read more »
*This blog post was originally published at Skeptic North*
November 30th, 2011 by PJSkerrett in Research
Tags: Blood Sugar, Diabetes, Glucose, Implantable sensor, insulin, Mayo Clinic, Medical Research, MIT, Nanosensors, Needles, Northeastern University, Research, Tattoo, Tears, Trials, UCSD, University of California-San Diego, University of Michigan
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My fingers hate diabetes. Several times a day they get poked with a sharp, needle-like lancet. The drops of blood they give up tell me how my blood sugar roller coaster is doing. That’s really important information I need to determine whether to eat, exercise, or give myself some insulin.
It would be such a treat to check my blood sugar (glucose) without pricking a finger, squeezing out a drop of blood, and placing it on a small test strip attached to a meter. Help may be on the way—though I’m not expecting any big breakthroughs for another few years—as researchers across the country explore prick-free ways to measure blood sugar.
Here are three interesting approaches. Read more »
*This blog post was originally published at Harvard Health Blog*
November 30th, 2011 by GruntDoc in Opinion, Research
Tags: Castlight, Charge, Cost, health care, Informed Decisions, Insurance, Policy, Price, runaway costs, Transparency, treatments
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I really like this idea, but … well, see after the quote.
It’s easy to compare prices on cameras, vacations, and homes. But in the United States, patients fly blind when paying for health care. People typically don’t find out how much any given medical procedure costs until well after they receive treatment, be it a blood draw or major surgery.
This lack of transparency has contributed to huge disparities in the cost of procedures. According to Castlight Health, a startup based in San Francisco, a colonoscopy costs anywhere from $563 to $3,967 within a single zip code. EKGs can range from $27 to $143, while the price for a set of three spinal x-rays varies from as little as $38 to as high as $162.
When someone else is picking up the tab, mystery pricing is not much of a problem. But these days, Read more »
*This blog post was originally published at GruntDoc*
November 29th, 2011 by Shadowfax in Research
Tags: Antiemetic, benzodiazepines, CVS, Cyclic Vomiting Syndrome, Drug-Seeking, Emergency Room, Evidence, Hydromorphone, Marijuana, Narcotics, Propofol, Research, Throwing up, Treatment, Vomit
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I have been working as an ER doctor for over a decade, and in that time I have come to recognize that there are certain complaints, and certain patients who bear these complaints, that are very challenging to take care of. I’m trying to be diplomatic here. What I really mean is that there are certain presentations that just make you cringe, drain the life force out of you, and make you wish you’d listened to mother and gone into investment banking instead. Among these, perhaps most prominently, is that of the patient with cyclic vomiting syndrome.
The diagnosis of cyclic vomiting syndrome, or CVS, is something which is only in recent years applied to adult patients. Previously, it was only described in the pediatric population. It has generally been defined as a disease in which patients will have intermittent severe and prolonged episodes of intractable vomiting separated by asymptomatic intervals, over a period of years, for which no other adequate medical explanation can be found, and for which other causes have been ruled out.
That is not much in the way of good literature about this disease entity, which is surprising, because it is something that I see in the emergency department fairly regularly, and something with which nearly all emergency providers are quite familiar. These patients are familiar to us in part because we see them again and again, in part because they are memorable because they are so challenging to take care of.
Some things about the cyclic vomiting patient that pose particular challenges: Read more »
*This blog post was originally published at Movin' Meat*
November 29th, 2011 by RyanDuBosar in Research
Tags: Aging, Archives of Ophthalmology, Cardiology, Cardiovascular Risk, carotid atherosclerosis, Disability, Eye, Microvascular changes, Research, Retina, retinal arteriolar caliber, Stenosis
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The idea that the eyes are a window to the soul traces back through history in many forms, but the idea that the eyes might reveal medical secrets didn’t fall far behind the metaphor.
The clues lie on the retina, which reflects the same microvascular changes that might be seen elsewhere in the body from cardiovascular changes and other diseases. The question now is how to associate retinal changes to specific diseases.
To assess potential associations between retinal microvascular changes with disability in performing activities of daily living, researchers conducted a prospective cohort study of 1,487 community-dwelling, disability-free participants in the Cardiovascular Health Study.
The main outcome measure was Read more »
*This blog post was originally published at ACP Internist*