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The Friday Funny: Why Evidence-Based Medicine Is Not The Whole Story

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Thanks to Harriet Hall, I found this hilarious spoof article from the BMJ which perfectly illustrates why “Evidence-Based Medicine” (EBM) alone is not sufficient for answering medical questions. The abstract perfectly illustrates why randomized controlled trials must be viewed within the context of general scientific knowledge rather than in isolation. The weakness of EBM has been an over-reliance on “methodolatry” – resulting in conclusions made without consideration of prior probability, laws of physics, or plain common sense.

EBM is valuable but not sufficient for drawing accurate conclusions… which is why Steve Novella and the Science Based Medicine team have proposed that our quest for reliable information (upon which to make informed health decisions) should be based on good science rather than EBM alone.

Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials

Gordon C S Smithprofessor1Jill P Pellconsultant2

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Could Sugar Pills Improve Smoking Cessation Rates?

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Professor Robert West, at University College London, has an interesting theory which suggests that glucose tablets can help smokers to quit. It is well known that when smokers quit smoking they put on weight, and that nicotine appears to act like a mild anorectic drug…it dulls the appetite. It has also been noted that smokers often crave high carbohydrate foods when they quit smoking. So it seems as though smoking dulls the hunger for carbohydrates. The glucose theory (or at least one version of it) suggests that when an addicted smoker quits smoking they experience a strong hunger/craving sensation, sometimes located in their stomach. When trying to interpret that sensation they think, “what am I craving? I just gave up cigarettes, it must be that.” Read more »

This post, Could Sugar Pills Improve Smoking Cessation Rates?, was originally published on Healthine.com by Jonathan Foulds, Ph.D..

42% Of Obese College Students Open Spam Emails About Weight Loss Products

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Most people automatically filter out spam e-mails, or delete them without ever opening them up.

But a surprising number of people actually take the time to read them, which is probably why annoying spam will continue unabated. From the New York Times’ Well, Tara Parker-Pope writes points an interesting study looking at who actually read health-related spam e-mails.

Looking at college students who were overweight, a study showed that an astounding 42 percent opened unsolicited e-mails touting weight loss products, and 19 percent actually ordered the product. And, perhaps more concerning, among those where were normal weight, 5 percent still bought what the spam was selling.

The effectiveness of spam e-mails, in this admittedly small study at least, certainly surprised me. I remember reading somewhere that it takes a success rate of 1 in 100,000 to make it worthwhile to a spam marketer.

But if they’re achieving success rates like these, it’s no wonder that the degree of spam, estimated to be 73 percent of all e-mails, will only rise.

That’s depressing.

*This blog post was originally published at KevinMD.com*

Post-Op Tips: A Preventive Strategy For Withdrawal Symptoms In Alcohol-Dependent Patients

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It has been a while since I’ve had a patient with postoperative alcohol withdrawal.  I can still recall my first exposure to this problem as a 3rd year medical student at the Veteran’s Hospital.  It was my first clinical rotation – surgery service at the VA.

Browsing the CME articles on the JAMA website, I came across the article (full reference below):  Improved Outcomes in Patients With Head and Neck Cancer Using a Standardized Care Protocol for Postoperative Alcohol Withdrawal.  For me it was a nice review of the problem with updates on current drug use/protocol.

Their protocol is based on three distinct clusters of symptoms characterize alcohol withdrawal syndrome (AWS). Central nervous system excitation usually occurs within 12 to 48 hours after the last drink. Read more »

*This blog post was originally published at Suture for a Living*

Larry Dossey, Premonition-Based Medicine, And The Bizarre Underbelly Of CAM

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A “Double Standard”?

Last week I had planned to write a comprehensive critique of a recent comment by Larry Dossey. He had posted it on Val Jones’s betterhealth website in response to Dr. Val’s essay, “The Decade’s Top 5 Threats To Science In Medicine,” originally posted here on SBM. Much of what Dr. Val had identified as the top threats involved recent dalliances, by government, medical schools, and the media, with the collection of implausible and mostly nonsensical health claims that advocates have dubbed “CAM.” As uncontroversial as Dr. Val’s assertions ought to have been—similar to suggesting that closing one’s eyes and “using the force” would be a threat to safe driving (even if some might quibble over the top threats to science in medicine)—Dr. Dossey demurred by distraction: Read more »

*This blog post was originally published at Science-Based Medicine*

Latest Interviews

IDEA Labs: Medical Students Take The Lead In Healthcare Innovation

It’s no secret that doctors are disappointed with the way that the U.S. healthcare system is evolving. Most feel helpless about improving their work conditions or solving technical problems in patient care. Fortunately one young medical student was undeterred by the mountain of disappointment carried by his senior clinician mentors…

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How To Be A Successful Patient: Young Doctors Offer Some Advice

I am proud to be a part of the American Resident Project an initiative that promotes the writing of medical students residents and new physicians as they explore ideas for transforming American health care delivery. I recently had the opportunity to interview three of the writing fellows about how to…

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Latest Book Reviews

Book Review: Is Empathy Learned By Faking It Till It’s Real?

I m often asked to do book reviews on my blog and I rarely agree to them. This is because it takes me a long time to read a book and then if I don t enjoy it I figure the author would rather me remain silent than publish my…

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The Spirit Of The Place: Samuel Shem’s New Book May Depress You

When I was in medical school I read Samuel Shem s House Of God as a right of passage. At the time I found it to be a cynical yet eerily accurate portrayal of the underbelly of academic medicine. I gained comfort from its gallows humor and it made me…

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Eat To Save Your Life: Another Half-True Diet Book

I am hesitant to review diet books because they are so often a tangled mess of fact and fiction. Teasing out their truth from falsehood is about as exhausting as delousing a long-haired elementary school student. However after being approached by the authors’ PR agency with the promise of a…

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