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Warfarin For Early Cancer Detection?

In cancer treatment, detection of a tumor in an early stage markedly increases the chance of favorable outcomes.  
Can the much-aligned blood thinner, warfarin, occasionally help in early detection of cancer?

Few pharmacologic agents receive more bad press than warfarin.  Stories, which are too numerous to count, like “Did warfarin kill my father,” can be widely found on Internet forums, search engines, and are often quoted by reluctant patients — whose numerator of bad warfarin experiences is one.

It is true that warfarin has a narrow therapeutic window — a small difference between an effective dose and dangerous dose. Read more »

*This blog post was originally published at Dr John M*

Sports On “Doctor Time”

We all know about “doctor time.” No matter how hard I try, the clock seems to out sprint me. Morning rounds in the hospital go longer than expected, a colleague stops you with a question, a son forgot his lunch, or something else. The list is long.

In fact, as a very well-educated patient, it seems that the doctors I choose for myself and family are even later than I. It seems that most good doctors have long waits. A coincidence?

However accepted “doctor time” is in the office or hospital, it doesn’t work the same in the bike racing world. In the land of genetically endowed androids, the clock waits for no one in particular. It turns out that our pizza-sponsored team has a few doctors who run on “doctor time” in real life. Read more »

*This blog post was originally published at Dr John M*

When Occam’s Razor Doesn’t Cut It

Occam’s razor is a well-known logical principle often applied in medicine. It states that the simplest explanation for a complaint or symptom is usually the correct one. Most of the time, Occam’s razor serves the diagnostician well, but when the actual problem is complex or unexpected, patients can be sent down expensive and even life-threatening diagnostic rabbit holes.

A friend of mine is an 80-pack-a-year smoker. He was complaining of shortness of breath, worsening over a couple of months, and his primary care physician sent him to a pulmonologist. The assumption was that the shortness of breath was related to COPD from his chronic smoking — and that indeed would have been the most likely explanation. Read more »

The Impact Of Attitude On Life

Life sometimes gets in the way of daily posting. Specifically, the treadmill of life sometimes roars too fast.

But as I strolled through the hospital this morning, there was a plain piece of white paper taped to the wall around the nurses station. Although I’m not overly religious (and even highly conflicted about which rituals are the right ones), these words from a pastor/celebrity stopped me for a moment:

Attitude

The longer I live, the more I realize the impact of attitude on life. Attitude, to me, is more important than facts. It is more important than the past, than education, than money, than circumstances, than failures, than success, than what other people think or say or do. It is more important than appearance, giftedness or skill.

It will make or break a company, a church, or a home. The remarkable thing is that we have a choice every day regarding the attitude we will embrace for that day.

We cannot change the past, we cannot change the fact that people will act in a certain way. We cannot change the inevitable. The only thing we can do is plan on the one thing that we have, and that is our attitude.

I am convinced that life is 10 percent what happens to me and 90 percent how I react to it.  And so it is with you. We are in charge of our attitudes.

As a cardiologist programmed to “alert” most of the time, words such as these help me. I haven’t seen the studies yet, but I’m guessing that positive attitudes reduce inflammation, which is good for our atria, and our arteries.

JMM

*This blog post was originally published at Dr John M*

“Short People Got No Reason” To Worry About Higher Heart Risk

“Short people have higher heart risk” screams the headline on CNN.com, treating it as a statement of fact. “Shortness Boosts Heart Disease, Death Risk” is the headline in a HealthDay story seen on BusinessWeek.com.

Wrong.

Such a study as the one being described can only establish association — it CANNOT prove causation. So it’s wrong to say short people have higher risk. It is wrong to say shortness boosts risk.

Blogger and cardiac electrophysiologist Dr. Wes Fisher beat me to the punch by blogging about the continued journalistic confusion between association and causation. He wrote:

“About the only thing that can be concluded from this so-called “analysis” is nothing more than maybe we should consider studying if this association actually exists.”

Tell ’em, Dr. Wes. And tell ’em, Randy: “Short people got no reason” to worry — at least not yet — from this study.

*This blog post was originally published at Gary Schwitzer's HealthNewsReview Blog*

Latest Interviews

IDEA Labs: Medical Students Take The Lead In Healthcare Innovation

It’s no secret that doctors are disappointed with the way that the U.S. healthcare system is evolving. Most feel helpless about improving their work conditions or solving technical problems in patient care. Fortunately one young medical student was undeterred by the mountain of disappointment carried by his senior clinician mentors…

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How To Be A Successful Patient: Young Doctors Offer Some Advice

I am proud to be a part of the American Resident Project an initiative that promotes the writing of medical students residents and new physicians as they explore ideas for transforming American health care delivery. I recently had the opportunity to interview three of the writing fellows about how to…

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Latest Book Reviews

Book Review: Is Empathy Learned By Faking It Till It’s Real?

I m often asked to do book reviews on my blog and I rarely agree to them. This is because it takes me a long time to read a book and then if I don t enjoy it I figure the author would rather me remain silent than publish my…

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The Spirit Of The Place: Samuel Shem’s New Book May Depress You

When I was in medical school I read Samuel Shem s House Of God as a right of passage. At the time I found it to be a cynical yet eerily accurate portrayal of the underbelly of academic medicine. I gained comfort from its gallows humor and it made me…

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Eat To Save Your Life: Another Half-True Diet Book

I am hesitant to review diet books because they are so often a tangled mess of fact and fiction. Teasing out their truth from falsehood is about as exhausting as delousing a long-haired elementary school student. However after being approached by the authors’ PR agency with the promise of a…

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