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Cancer Pathology: Are Lab Tests Always Right?

The Wall Street Journal’s Health Blog says that cancer lab tests “aren’t always right.” They report on reports issued by two professional societies that point out that as many as 20% of a certain kind of test are inaccurate. According to the Health Blog the problem is the tests “aren’t black and white, and rely on a pathologist’s judgment.”

Now, judgment is a critical factor in most everything in medicine, but perhaps nowhere else are the consequences of incorrect judgment so serious as in pathology. As Dr. William Osler famously observed: “As is your pathology, so goes your clinical practice.” But how widespread is this problem? Read more »

*This blog post was originally published at See First Blog*

Pro-Test: Human Lives Improved By Responsible Animal Research

[On April 8th] at the University of California at Los Angeles, a rally [was] planned to raise awareness about the value of responsible animal research and to denounce acts of terrorism toward animal researchers and their families. The highlight of the “Pro-Test” rally [was] the presentation to legislators and the media a petition with nearly 12,000 signatures of scientists who support the use of animals in research.

The rally and the petition drive [was] a joint effort of Americans for Medical Progress, Pro-Test for Science, and Speaking of Research.

I stand together with my colleagues who conduct animal research in honor of their application of knowledge to advance biology and relieve human suffering, all while a growing movement of animal rights activists up the ante from protests to attacks on researchers, destruction of homes by arson, and even the vandalism of graves of researchers’ loved ones. Read more »

*This blog post was originally published at Terra Sigillata*

Confidence And Doubt: The Language Of Clinician Versus Researcher

There’s an adage I often think about: “A physician’s job requires the expression of confidence. The researcher’s role is to express doubt.”

This was never more apparent than when I transitioned from the research environment into the clerkships of medical school. The language of decision-making had abruptly changed — in the lab, a year’s worth of experiments is summarized with “seems” and “suggests,” and every assertion is carefully calibrated to acknowledge uncertainty and a high standard for proof.

As a student on clerkships, I couldn’t quite wrap my head around the residents’ ambitious plans for patients: Read more »

*This blog post was originally published at Blogborygmi*

When A Crazy Patient Is Actually Right

Sometimes in this job you just get lucky.  You have an elusive and/or dangerous diagnosis just dropped in your lap.  Something devastating that you would never have been able to tease out otherwise just gets handed to you by the patient.  There’s a catch, though: you have to be smart enough to know when to listen to the patient, when not to blow off their crazy talk as just crazy.

So it was recently when I saw a guy with back pain.  From the chart, it didn’t sound like anything complex: a middle-aged to older guy, maybe 60 or so, with a history of chronic back pain and multiple surgeries for the same.  He was on Oxycontin 80 mg three times daily (a very high dose, and a red flag for an ER doc naturally suspicious of drug-seeking behavior).  I went to see him, and it was clear in seconds that this dude was JPN: Just Plain Nuts. Read more »

*This blog post was originally published at Movin' Meat*

Physicians, Technophobia, And Costly Communication Gaps

I was talking to a fellow physician about a mutual patient.  I had information  that would help him in their care and he was taking the unusual step of asking me for my information.  I was impressed.

“Could you fax me those documents?” he asked.  ”Here’s my fax number.”

I scrambled to get a pen to write down his number.  Then I had a thought: “I could email you those documents much easier.  Do you have an email address?”

Silence.

After a long pause, he hesitantly responded, “I would rather you just fax it.”  He said no more. Read more »

*This blog post was originally published at Musings of a Distractible Mind*

Latest Interviews

IDEA Labs: Medical Students Take The Lead In Healthcare Innovation

It’s no secret that doctors are disappointed with the way that the U.S. healthcare system is evolving. Most feel helpless about improving their work conditions or solving technical problems in patient care. Fortunately one young medical student was undeterred by the mountain of disappointment carried by his senior clinician mentors…

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How To Be A Successful Patient: Young Doctors Offer Some Advice

I am proud to be a part of the American Resident Project an initiative that promotes the writing of medical students residents and new physicians as they explore ideas for transforming American health care delivery. I recently had the opportunity to interview three of the writing fellows about how to…

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Latest Book Reviews

Book Review: Is Empathy Learned By Faking It Till It’s Real?

I m often asked to do book reviews on my blog and I rarely agree to them. This is because it takes me a long time to read a book and then if I don t enjoy it I figure the author would rather me remain silent than publish my…

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The Spirit Of The Place: Samuel Shem’s New Book May Depress You

When I was in medical school I read Samuel Shem s House Of God as a right of passage. At the time I found it to be a cynical yet eerily accurate portrayal of the underbelly of academic medicine. I gained comfort from its gallows humor and it made me…

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Eat To Save Your Life: Another Half-True Diet Book

I am hesitant to review diet books because they are so often a tangled mess of fact and fiction. Teasing out their truth from falsehood is about as exhausting as delousing a long-haired elementary school student. However after being approached by the authors’ PR agency with the promise of a…

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