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Treatment-Resistant Depression: New Insights

Only one-third of people with major depression achieve remission after trying one antidepressant. When the first medication doesn’t adequately relieve symptoms, next step options include taking a new drug along with the first, or switching to another drug. With time and persistence, nearly seven in 10 adults with major depression eventually find a treatment that works.

Of course, that also means that the remaining one-third of people with major depression cannot achieve remission even after trying multiple options. Experts are hunting for ways to understand the cause of persistent symptoms. In recent years, one theory in particular has gained traction: that many people with hard-to-treat major depression actually suffer from bipolar disorder. However, a paper published online this week in the Archives of General Psychiatry suggests otherwise — and the findings provide new insights into the nature of treatment-resistant depression. Read more »

*This blog post was originally published at Harvard Health Blog*

Prison Overcrowding: Does It Affect Mental Health?

In California, the U.S. district court has ordered that tens of thousands of prisoners be released to reduce overcrowding. The case, Schwarzenegger v. Plata, was argued this past Tuesday and the transcript is online.

This is relevant to a psychiatry blog because one of the arguments used in support of the releases is the contention that overcrowded facilities reduce access to mental health and medical services and that overcrowding causes mental deterioration and breakdown. The APA filed an amicus brief in the case, but the brief isn’t available online yet. (Keep an eye out for it here.)

The challenge with this case is that there is no (or extremely little) actual research to support the link between overcrowding and psychological problems. Correctional systems have spent a lot of time litigating issues — and experts make a fair amount of money working on these cases — without actual data. Read more »

*This blog post was originally published at Shrink Rap*

Narcissism: No Longer A Personality Disorder?

Via an article in The New York Times entitled “Narcissism No Longer a Psychiatric Disorder”:

Narcissistic personality disorder, characterized by an inflated sense of self-importance and the need for constant attention, has been eliminated from the upcoming manual of mental disorders, which psychiatrists use to diagnose mental illness.

As Charles Zanor reports in today’s Science Times, the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders — due out in 2013 and known as D.S.M.-5 — has eliminated five of the 10 personality disorders that are listed in the current edition. The best known of these is narcissistic personality disorder.

So, blogging is normal then? Kinda takes the fun out of it…

*This blog post was originally published at GruntDoc*

Psychotherapy And Humor

Awhile back I put up a YouTube audio that I thought was funny. A commenter didn’t like it and felt it promoted stigma. So I took a vote, and while most people were fine with it, a number did not like it, and I took the post down. We received this note, and I thought it was substantial enough to be its own guest post (with permission, of course).
——————

Hi. I am a practicing psychiatrist based in New York City. I find your blog interesting, informative, and, at times, funny. Now, can you guess which entry I’d like to comment on?

Mel Brooks once said (paraphrased) that if you slip on a banana peel and land on your butt, it’s comedy. If I fall down a flight of stairs, it’s tragedy. I’ve had a long-term interest in humor, and a brief career as an unpaid stand-up comic in L.A. (Brief because my bombing to “killing” ratio was about 15 to one.) With respect to my experience as a therapist, I now occasionally utilize humor in my treatment, but only extremely judiciously once I have gotten to know my client. I learned my lesson early.

At the beginning of my residency training, during my second session with a client, I commented that perhaps he felt like Groucho Marx when Groucho said that he “wouldn’t want to be a member of any club with standards low enough to accept [him].” I sat back, feeling as if I had made the interpretation of the century, and waited for a reaction. I got one. Read more »

*This blog post was originally published at Shrink Rap*

Give A Microloan, Get Healthier

Research has shown that giving to others can lead to a healthier, happier, and longer life. Generous behavior reduces depression and risk of suicide in adolescents.  Volunteerism on the part of older adults significantly reduces mortality. Giving to others enables people to forgive themselves for mistakes — a key element in well-being.

One way to have a lot of fun on the Internet and get a health boost while doing so is to log on to a cool site called Kiva. For as little as $25.00, ordinary people like you and me can be part of the worldwide microloan (or microcredit) community. Kiva’s mission is to connect people through lending for the sake of alleviating poverty. Read more »

*This blog post was originally published at EverythingHealth*

Latest Interviews

IDEA Labs: Medical Students Take The Lead In Healthcare Innovation

It’s no secret that doctors are disappointed with the way that the U.S. healthcare system is evolving. Most feel helpless about improving their work conditions or solving technical problems in patient care. Fortunately one young medical student was undeterred by the mountain of disappointment carried by his senior clinician mentors…

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How To Be A Successful Patient: Young Doctors Offer Some Advice

I am proud to be a part of the American Resident Project an initiative that promotes the writing of medical students residents and new physicians as they explore ideas for transforming American health care delivery. I recently had the opportunity to interview three of the writing fellows about how to…

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Latest Book Reviews

Book Review: Is Empathy Learned By Faking It Till It’s Real?

I m often asked to do book reviews on my blog and I rarely agree to them. This is because it takes me a long time to read a book and then if I don t enjoy it I figure the author would rather me remain silent than publish my…

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The Spirit Of The Place: Samuel Shem’s New Book May Depress You

When I was in medical school I read Samuel Shem s House Of God as a right of passage. At the time I found it to be a cynical yet eerily accurate portrayal of the underbelly of academic medicine. I gained comfort from its gallows humor and it made me…

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Eat To Save Your Life: Another Half-True Diet Book

I am hesitant to review diet books because they are so often a tangled mess of fact and fiction. Teasing out their truth from falsehood is about as exhausting as delousing a long-haired elementary school student. However after being approached by the authors’ PR agency with the promise of a…

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