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Conflicts Of Interest Within Clinical Trials Can Jeopardize The Participants

Follow the money.

Earlier this week, I blogged about the growing economic relationships and even mutual dependency between medical device manufactures and physicians, citing a pre-emptive strike against an Institute of Medicine report that recommended closer regulation of medical devices before and after they enter the market. Such ties, though, are only one part of a broader medical-industrial complex that has enormous impact on public policy in the United States.

A 2009 White Paper by the Seton Hall’s Center for Health & Pharmaceutical Law & Policy reported that “ drug and medical device companies fund up to 80% to 90% of all clinical trials; in 2005, and that by 2004, three-quarters of all of the clinical trials paid for by industry were in private physician practices or for-profit research centers.” The paper’s authors argue that such trials “create potential conflicts of interest that possibly jeopardize the rights and well-being of research participants as well as the integrity of research results” and that “the goal for public policy should be to structure physician-investigator payment to achieve financial neutrality between treatment and research.”

A recent web posting by a medical billing company unabashedly crows about the extra income doctors can make from clinical trials. Read more »

*This blog post was originally published at The ACP Advocate Blog by Bob Doherty*

Great Clinical Care And Excellent Bedside Manner: Are They Mutually Exclusive?

The New York Times recently published an article titled, Finding a Quality Doctor, Dr. Danielle Ofri an internist at NYU, laments how she was unable to perform as well as expected in the areas of patient care as it related to diabetes.  From the August 2010 New England Journal of Medicine article, Dr. Ofri notes that her report card showed the following – 33% of patients with diabetes have glycated hemoglobin levels at goal, 44% have cholesterol levels at goal, and a measly 26% have blood pressure at goal.  She correctly notes that these measurements alone aren’t what makes a doctor a good quality one, but rather the areas of interpersonal skills, compassion, and empathy, which most of us would agree constitute a doctor’s bedside manner, should count as well.

Her article was simply to illustrate that “most doctors are genuinely doing their best to help their patients and that these report cards might not be accurate reflections of their care” yet when she offered this perspective, a contrary point of view, many viewed it as “evidence of arrogance.”

She comforted herself by noting that those who criticized her were “mostly [from] doctors who were not involved in direct patient care (medical administrators, pathologists, radiologists). None were in the trenches of primary care.”

From the original NEJM article, Dr. Ofri concluded Read more »

*This blog post was originally published at Saving Money and Surviving the Healthcare Crisis*

Oncologist Considers Heat-Based Cancer Treatment

There’s so much weird and exciting cancer news this week, it’s hard to keep up!

Double-kudos to Andrew Pollack on his front-page and careful coverage in the New York Times of the hyperthermic intraperitoneal chemotherapy (Hipec) technique that’s being used at some name-brand health care facilities to treat colon cancer.

First, he spares no detail in the Times describing the seemingly primitive, crude method:

….For hours on a recent morning at the University of California, San Diego, Dr. Andrew Lowy painstakingly performed the therapy on a patient.

After slicing the man’s belly wide open, Read more »

*This blog post was originally published at Medical Lessons*

Patients Are Rejecting Valuable Treatment Based On False Information

Newsweek has a very provocative and yet incredibly too simplistic piece for the public and patients on its cover story – One Word Can Save Your Life: No! – New research shows how some common tests and procedures aren’t just expensive, but can do more harm than good.

The piece is actually well written and highlights facts that have been apparent for some time.  More intervention and treatment isn’t necessarily better.  Having a cardiac catheterization or open heart surgery for patients with stable heart disease and mild chest pain isn’t better than diet, exercise, and the prescription medication treatment.  PSA, the blood test previously suggested by many professional organizations, isn’t helpful to screen for prostate cancer, even though the value of the test was questioned years ago.  Antibiotics for sinus infection?  Usually not helpful.

Certainly doctors do bear part of the blame.  If patients are Read more »

*This blog post was originally published at Saving Money and Surviving the Healthcare Crisis*

New Cancer Treatment Gains Momentum

You heard about it first on Patient Power when, a couple of years ago, we interviewed Dr. Andrew Lowy, oncology surgeon at UC San Diego Medical Center. He explained how some patients with advanced cancer spread in their abdomen could benefit from an open surgery – perhaps as much as nine hours long – where, after snipping out visible cancer – the organs are bathed in heated chemotherapy for 90 minutes. You may recall the story of Jennifer Ambrose, a young mom from suburban Chicago, who developed cancer of the appendix. She tracked down Dr. Lowy after spotting him on the Internet. She traveled to San Diego, had the “hot chemo” procedure, recovered and then went on to have a second child – her “miracle baby.” Today Jennifer remains fine and her story is featured in my book, The Web-Savvy Patient.

Jennifer Ambrose’s Powerful Patient Video

Today Andrew Pollack, reporter for The New York Times, wrote a front page story about Dr. Lowy, hot chemo, and how other medical centers are now picking up on it for other advanced cancers including colon and ovarian. They are even advertising it as one last bit of hope when often there is virtually none. Now, some of the big names in GI cancers are suggesting this approach has merit and may offer longer survival then some super expensive drugs. There’s a debate going on. Read more »

*This blog post was originally published at Andrew's Blog*

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