July 11th, 2008 by Dr. Val Jones in News
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The Wall Street Journal recently described some interesting new research related to the early detection of autism. Some scientists suggest that babies at risk for developing autism have different facial-scanning eye movement patterns. In other words, babies tend to focus on the eyes and mouth of faces in their direct line of sight. Babies at risk for developing autism have difficulty recognizing faces and their eyes may tend to wander. Although this test is not a diagnostic tool, it could be used to predict risk as early as 9 months – which could allow parents to get their children into early intervention programs sooner than they do now.
Researchers at Canada’s McMaster University recently announced that they had developed a computerized test using eye-movement sensors that aims to predict the risk of autism in children as young as 9 months. The system, which administers five eye-tracking tests over 10 minutes, measures the direction and fixation of a child’s eyes when confronted with computerized images, including human faces.
“Children with autism in general have difficulty extracting affective information from faces, and also difficulty in recognizing faces,” says Katarzyna Chawarska, director of the Yale clinic. By tracking eye movements, “we can begin to understand what interests them, how they examine objects they select for processing, and what motivates them intrinsically,” she says.
But eye-tracking won’t pick out all children with autism. That’s because the disorder can manifest itself in a variety of ways at different ages, such as a child not responding when called or failing to exhibit normal body gestures. Some children also won’t cooperate with the eye-tracking equipment.
I think it’s too early to know how valuable this tool will be in the evaluation of children at risk for autism spectrum disorders, but it’s certainly an interesting idea.
This post originally appeared on Dr. Val’s blog at RevolutionHealth.com.
July 9th, 2008 by Dr. Val Jones in Celebrity Interviews, Expert Interviews
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I had the pleasure of interviewing Jeanette Bolden, US women’s track and field coach for the Beijing Olympics, about her life-long struggle with asthma and her thoughts on the upcoming Olympics. We were joined by her physician, Dr. Bobby Lanier, on a fascinating call about how the environment in Beijing might affect Olympic athletes and visitors to China.
*Listen to the podcast*
Dr. Val: What was it like growing up with severe asthma? How did you cope?
Bolden: I’ve had asthma all my life, and unfortunately, when I was young my mom used the Emergency Department as the primary source of treatment for my asthma. So I was in and out of the emergency room all the time and my asthma was really out of control. Things got so bad that I was actually sent to a home for asthmatic children, where I had to live for 9 months – away from my family. I did learn how to manage my asthma with the help of the people at the home, and learned to be much less afraid of it.
However, I had problems with other kids picking on me because of my illness. I used to carry my inhaler in my sock and one time it fell out and a boy picked it up and started spraying it all over the place and shouting “asthma face” and “spasma girl” and he would tell others not to play with “asthma girl.”
Dr. Val: What got you interested in track and field? Did anyone discourage you from athletics because of your asthma?
Bolden: When I returned from the home for asthmatic children, I was a pretty normal kid – and I liked to run and play outdoors. One day I was with my younger sister at a park and we met a local track and field coach – so I asked if I could join his team. I told him that I had asthma and was worried that he wouldn’t want me on the team. However, he really surprised me and simply said, “If it doesn’t bother you, it doesn’t bother me.”
Although my dad was worried about me running and having a potential asthma attack, my mom always encouraged me to do my best and not let it hinder me.
Once I started winning races, my asthma became more acceptable. I don’t think I would have accomplished as much in my career if I didn’t have asthma – because it drove me to strive harder to prove myself to others and to show those kids who picked on me that nothing would stop me from excelling.
Dr. Val: How did you manage your asthma when you were at the 1984 Olympics?
Bolden: I had to submit a letter to the United States Olympic committee about my asthma, along with a note from my doctor about the medications I was taking. I always kept my inhaler nearby (though not necessarily in my sock) and tried to stay away from things that I was allergic to.
Dr. Val: What was the turning point for you – to get your asthma under control?
Bolden: My doctors always told me that I’d outgrow my asthma. I’m now 48 years old and still have it. And it wasn’t until lately that I understood that I have a specific type of asthma, called allergic asthma, which responds really well to a new medicine called Xolair (omalizumab). That medicine has made a real difference for me.
Dr. Val: Dr. Lanier, can you explain a little bit about monoclonal antibodies and how they’re now being used to reduce asthma symptoms?
Dr. Lanier: We’ve had effective medicines for the treatment of asthma for a long time, but a lot of them rely on inhaled steroids, which are not healthy for people (especially women) to take long term. So research has focused on getting to the root cause of asthma. About 60% of people who have asthma also have allergies – and we refer to this as “allergic asthma.” Allergies are caused primarily by a certain type of antibody in the blood stream known as IgE (immunoglobulin E). The “Holy Grail” of asthma treatment is to find a way to selectively cripple IgE without affecting the rest of the body.
Xolair is a targeted therapy that sticks to IgE and removes it from the body. It’s like taking away the fuel for the allergic process and this dramatically helps some people.
Dr. Val: Are there any risks associated with Xolair?
Dr. Lanier: There have been reports of people having an allergic reaction to Xolair, but I’ve never seen a patient with this problem, and I’ve treated hundreds of people with the medication. However, I’m always careful to watch out for a potential reaction. In my opinion the risks associated with Xolair are lower than those of standard therapy (steroids) – and when you’re removing IgE from the system, you’re really attacking the disease at its root.
Dr. Val: Jeanette, how did you become the coach of the 2008 women’s track and field team?
Bolden: I was voted to be the coach by my peers in track and field. There are criteria that they use for the selection process, and eligible candidates must have 1) been an Olympian 2) been a coach for a number of years 3) coached Olympians. There is an Olympic coach committee that handles the selection process and I’m pleased that they chose me. My commitment lasts three years and is over on the last day of the Olympics, 2008.
Dr. Val: What is the “asthma on track” program?
Bolden: It’s a fantastic online resource for people to learn more about allergic asthma, IgE testing, and how to find a specialist who can help. People can also learn more about my story on the website. I think education is really important because it’s the only way to free yourself from the fear of an asthma attack. My hope is that this website will teach people with allergic asthma that they don’t have to sit on the sidelines and watch life pass them by. The proper treatment program can put people back in control of their lives so they can train to become Olympians if they want to. And for me, the proper therapy has allowed me to enjoy having my dog live in the house with me for the first time. This makes both of us really happy.
Dr. Val: Do any of this year’s US women’s track and field team members have asthma?
Bolden: Asthma is the leading cause of absenteeism among school age kids. I’m sure that there will be individuals who make the team and also have asthma.
Dr. Val: Tell me about the environmental conditions in Beijing – what are you worried about as a coach?
Bolden: We’ve all heard about the pollution problem – though the Chinese government has scheduled factory and industrial shut downs many months prior to the Olympics. I really think that the main issues are the heat and the humidity, though. And since the Olympic trials are being held in Eugene, Oregon – where it’s been really hot and humid – the athletes will be well-prepared for Beijing.
Dr. Val: Dr. Lanier – as a physician, what are your concerns about environmental risks to Olympians in Beijing this summer?
Dr. Lanier: I don’t think the environmental risks are going to be as great as some think. If you look at historical paintings of Beijing dating back hundreds of years, you’ll always see a foggy cloud around it. That’s just the microclimate of that area of the world. However, there has been significant construction in the area recently – half the steel in the world went to China last year and a lot of that went to Beijing.
I’ve been going to Beijing multiple times a year for 10-15 years now, and although the construction effort has been extensive, I think that with the steps that the Chinese government is taking to improve air quality will make a big difference. It’s also interesting that the incidence of asthma in China overall is much lower than it is in the United States.
Dr. Val: Are visitors with allergic asthma at risk of having flare ups in Beijing?
Dr. Lanier: I think they actually have a lower risk than they would inside the United States. Allergic reactions are a defensive response from the body, and ordinarily that requires that you’ve had a prior exposure to the allergen. People going to Beijing for the first time have never been exposed to their native pollens, so I think the allergic asthma issues will be greatly reduced.
However the heat and humidity, exercise-induced asthma, and upper respiratory tract infections (that come from large crowds of people being in close contact) could all be problematic in Beijing.
Dr. Val: What general medical advice do you have for people traveling to Beijing?
Dr. Lanier: The most important thing for travelers (no matter where they’re flying) is to carry their medications with them in their carry-on luggage. Don’t take your pills out of their original bottles, because you may need the exact prescription labels. That way, even if your luggage is lost, you won’t miss any doses of medicine.
There are some vaccines that are recommended for people traveling to China, so people should check with their doctors before they go.
As far as food is concerned, I think that people will be pleasantly surprised by the variety and quality of food available. Food borne illnesses like salmonella are not common in Beijing, but I can’t speak for the surrounding countryside. Of course, it’s always wise to drink bottled water and not eat unwashed foods that may have been handled by many individuals – like grapes for example.
Dr. Val: Do you have any final thoughts about Beijing?
Bolden: I’m looking forward to a fantastic Olympic games. We have so many wonderful Olympic athletes this year – I just know it’s going to be great.
***
Jeanette Bolden is the head coach of the 2008 U.S. Olympic Women’s Track & Field team and the head coach at UCLA, her alma mater. At the 1984 Los Angeles Olympics, she won gold in the sprint relay despite a life-long struggle with asthma. Jeanette is preparing her team of athletes to compete in Beijing this summer – a city known for its asthma-inducing pollution.
Dr. Bobby Lanier, is a Clinical Professor in the Department of Pediatrics & Immunology at North Texas University Health Science Center and a Clinical Professor of Allergy and Immunology at Peking Union Medical College in Beijing. As a former NBC reporter, Dr. Lanier produced and appeared in over 5000 daily nationally syndicated broadcast radio and television segments. He is currently working on a book entitled The New Epidemic: A Patient Survival Guide to Asthma.
*Listen to the podcast*This post originally appeared on Dr. Val’s blog at RevolutionHealth.com.
July 2nd, 2008 by Dr. Val Jones in Celebrity Interviews, Expert Interviews
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Would you know what to do if someone in your office collapsed in front of you and became unresponsive? Having a defibrillator handy could save their life – and it’s important for you to know how to use one. I interviewed Dr. Jon LaPook, Medical Correspondent for CBS Evening News with Katie Couric, to get his take. [Interesting factoid: Jon became passionate about cardiac defibrillators after a friend of his died while exercising at a gym in NYC. The health club did not have a defibrillator on site – which could have saved his friend’s life.]
*Listen to the podcast*
Dr. Val: What is a defibrillator?
Dr. LaPook: It’s a machine that can convert a life threatening heart rhythm (like ventricular tachycardia or ventricular fibrillation) back into a normal beating pattern. It uses a pulse of electricity to do this. These machines are potentially life-saving.
Dr. Val: Why is it important for offices to have them on hand?
Dr. LaPook: About 1.2 million people in the United States have a heart attack every year and 300,000 of those have “sudden death.” The reason why these people die is not because of the heart attack, but because of the irregular heart rhythm that accompanies it. When the heart isn’t beating in a coordinated fashion, it can’t pump blood effectively and people pass out and ultimately die if there’s no intervention.
If a defibrillator is used to administer a shock to the chest during one of these life threatening heart rhythms, there’s a much higer chance that the person’s life will be saved. For every minute of delay (from the time a person collapses) to receiving a shock to the chest, their chance of survival decreases by 7-10%. So it’s very important for people to get defibrillation quickly.
Dr. Val: How do you use a defibrillator?
Dr. LaPook: When you first see someone collapse and become unresponsive, all you have to do is get the defibrillator and press the “on” switch. It will talk you through the next steps. Remember that the first step is always to have someone call 911 so that EMS will be on its way while you continue CPR. Then you expose the victim’s chest so that you can apply two sticky pads, and the defibrillator will tell you where to put the pads. Then it will analyze the victim’s heart rhythm and decide if it requires a shock to get it beating in a coordinated way. If a shock is recommended, the machine will announce that and ask you to step away from the person. Once the shock has been received, it will then give you instructions for CPR (which includes chest compressions and rescue breaths) until EMS arrives or a pulse is able to be felt. If a person doesn’t require a shock, the machine will not give one – so there’s no risk of harm to the victim.
It’s important for people not to be intimidated about defibrillation because it’s really very simple and can save a life.
Dr. Val: What are a person’s chances of surviving a cardiac arrest?
Dr. LaPook: Nationally, your chances of survival (without intervention) are about 4-6%. If you receive CPR, your chances increase to 15% but with a defibrillator – especially if it’s used quickly – the chances are 40% or higher.
Dr. Val: What do you think about the new research suggesting that rescue breaths may not be as important for CPR as initially thought?
Dr. LaPook: I spoke to Dr. Rose Marie Robertson, who is the Chief Science Officer at the American Heart Association, and she said that in a “witnessed arrest” (when you actually see someone collapse) it doesn’t seem to make a {big} difference if you do rescue breathing (i.e. mouth-to-mouth resuscitation) or not. The reason they studied this is because one of the main reasons why people don’t perform CPR is the “ick” factor of mouth-to-mouth resuscitation. As it turns out, chest compressions alone are about as successful at saving lives as traditional CPR. However, if you’ve been trained to do the rescue breathing technique, you should definitely use it. The key to CPR is “hard and fast” chest compressions, about 100 compressions per minute. Whatever form of CPR you use, the key to success is using the defibrillator as soon as possible, ideally within several minutes.
Dr. Val: What should people working in an office environment know about first aid?
Dr. LaPook: The most important thing is for people to be trained in CPR, the Heimlich maneuver, and defibrillator use.
Dr. Val: Are there enough defibrillators out there nowadays?
Dr. LaPook: Not at all. At the very least, defibrillators should be in every single health club in America. I also think they should be installed in every office building and be widely available at schools.
A cardiologist friend of mine told me about some parents who lobbied for their daughter’s school to purchase a defibrillator. (They were in tune to cardiac issues in children because their daughter had an arhythmia called Wolff-Parkinson-White syndrome.) Two years after the school purchased the device, the girl – only 13 years old at the time – collapsed while walking past the nurse’s office at the school. The nurse saved her life with the very defibrillator that her parents fought so hard for. So defibrillators are incredibly important, and although they’re not inexpensive (about $1200), you really can’t put a price on life.
*Listen to the podcast*
*Check out Dr. LaPook’s defibrillator training video with Katie Couric*This post originally appeared on Dr. Val’s blog at RevolutionHealth.com.
June 30th, 2008 by Dr. Val Jones in Opinion
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As newly minted physicians begin their residency training and clinical care responsibilities on July 1, hospitalized patients might expect a bumpy transition. At least, that’s been the urban legend – “don’t get sick in July!” But is that really true? Are patients at higher risk for medical errors at teaching hospitals in July?
Some say, “no” and some say “yes.” I’m in the “yes” category, and some research suggests that medication error rates do in fact increase in the month of July. In the “no” category we have Jerome Groopman, renowned Harvard physician and author of “How Doctors Think.” He simply says, “Today, most hospitals closely watch over interns.”
This is what I wrote in a previous blog post:
There are many ways that an intern can make mistakes, without ordering a single test or procedure, and under the full scrutiny of red tape regulations and documentation practices.
When an intern fails to recognize a life threatening condition and chooses to do nothing, or to let the patient wait for an extended period of time before alerting his or her team to the issue, serious harm can befall that patient. And that harm is not caused by inexperienced procedural technique, or ordering the wrong medicine – it’s caused by doing nothing. This “doing nothing” is the most insidious of intern errors – and it is not remedied by any form of hospital quality improvement initiatives. It is the risk that a hospital takes by having inexperienced physicians in the position of first responders. Interns gather large amounts of information about patients and then create a summary report for their supervisors. The supervisors (more senior residents) don’t have time to fact check every single case, and must rely on the intern’s priority hierarchy for delivering care.
But many hours pass between the time an intern examines a patient and when a supervising physician checks back in with that patient. And within that period of time, many conditions can deteriorate substantially, resulting in the loss of precious intervention time.
Dr. Groopman describes an experience from his own life in which a surgical intern (in July) correctly diagnosed his son with an intussusception
(twisted bowel) but then incorrectly determined that the baby could wait to go to the O.R. Of course, untreated intussusceptions are nearly always fatal, and each minute that passes without intervention can increase the risk of death.
And so, in my opinion, it is in fact more dangerous to be admitted to a teaching hospital in July, but not necessarily for the reasons that people assume (procedures performed by inexperienced physicians or drug errors – though those mistakes can be made as well). Rather, it is because interns don’t have the clinical experience to know how to prioritize their to-do lists or when to notify a superior about a patient’s health issue. Timing is critically important in quality care delivery – and that variable is not controlled by our current intern oversight system.
Now that I’ve completely terrified you – I will offer you a word of advice: designate a patient advocate for your loved one (or yourself) if you have to be in the hospital as an inpatient (especially in July). If you can, find someone who is knowledgeable about medicine – and who knows how to navigate the hospital system. A nurse, social worker, or physician are great choices. That person will help you ensure that concerns are prioritized appropriately when your intern doesn’t yet fully appreciate the dangers behind certain signs symptoms. If you have no advocate, then befriend staff members who are particularly caring and experienced. Be very nice to them – but don’t be afraid to insist on being examined by the intern’s supervisor if you really are concerned. Unfair as it may seem, sometimes the most vocal patients get the best care.
This post originally appeared on Dr. Val’s blog at RevolutionHealth.com.
