October 31st, 2011 by RyanDuBosar in Research
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Providing information of imminent death to cancer patients does not increase pain or anxiety, but is associated with improved care and to increase the likelihood of fulfilling the principles of a good death, a Swedish study found.
Informed patients significantly more often had parenteral drugs prescribed as needed, died in his or her preferred place, and had an informed family who were offered bereavement support. There was no difference between informed and uninformed patients in control of pain, anxiety, nausea, and respiratory tract secretions, although there was a difference in management of confusion. Results appeared in the Journal of Clinical Oncology.
Since 2000, there has been an increasing focus on palliative care in Sweden, the study authors wrote. In 2001, the Swedish Government identified breakpoints for Read more »
*This blog post was originally published at ACP Hospitalist*
July 16th, 2011 by Medgadget in News
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Clinicians at Karolinska University Hospital in Sweden are reporting that they successfully performed the world’s first implantation of a synthetic trachea. The organ was created from a biocompatible scaffold that was seeded with the 36 year old patient’s own stem cells inside a Harvard Bioscience bioreactor.
The patient had been suffering from late stage tracheal cancer. Despite maximum treatment with radiation therapy, the tumor had reached approximately 6 cm in length and was extending to the main bronchus. It was progressing and almost completely blocked the trachea. Since no suitable donor windpipe was available, Read more »
*This blog post was originally published at Medgadget*
October 25th, 2010 by Debra Gordon in Better Health Network, Health Policy, Opinion, Research
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I spent last week in Gothenburg, Sweden covering the European Committee for the Treatment of Multiple Sclerosis (ECTRIMS) meeting. Lots of good science, lots of excitement over the new oral and targeted therapies coming on the market to treat this awful disease. But what I want to write about isn’t the science, but about how it will play out in the brave new world of healthcare in which we all live in today.
For instance, consider the first oral therapy to hit the market: Gilenya (fingolimod), which the FDA approved in September. Last month Novartis announced the price: $48,000 a year.
This is not a rant against the high cost of drugs, however. It is a rant against the inability of our healthcare system to take the long view of the impact of such drugs, a view that is particularly important with a chronic disease like MS that strikes healthy young adults in their early 20s and 30s. Read more »
*This blog post was originally published at A Medical Writer's Musings on Medicine, Health Care, and the Writing Life*
August 31st, 2010 by Medgadget in Better Health Network, News, Research
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Researchers at Lund University in Sweden successfully used magnets to guide clot-dissolving drugs (fibrinolytics) directly to the site of a thrombus stuck within a coronary stent. They did this by attaching the drugs to magnetic nanoparticles and using external magnets to move them to the right spot.
From the press release:
Guiding drug-loaded magnetic particles using a magnet outside the body is not a new idea. However, previous attempts have failed for various reasons: It has only been possible to reach the body’s superficial tissue, and the particles have often obstructed the smallest blood vessels.
The Lund researchers’ attempt has succeeded partly because nanotechnology has made the particles tiny enough to pass through the smallest arteries and partly because the target has been a metallic stent. When the stent is placed in a magnetic field, the magnetic force becomes sufficiently strong to attract the magnetic nanoparticles. For the method to work the patient therefore has to have an implant containing a magnetic metal.
Press release: Medicine reaches the target with the help of magnets…
Abstract in Biomaterials: The use of magnetite nanoparticles for implant-assisted magnetic drug targeting in thrombolytic therapy.
*This blog post was originally published at Medgadget*
May 25th, 2010 by CynthiaHainesMD in Better Health Network, Health Tips, Research
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“I never worry about action, but only about inaction.” — Winston Churchill
Winston Churchill was right: Experts are saying sedentary behavior is an epidemic, with the resulting health effects potentially devastating.
Lack of muscular activity is associated with higher incidence of obesity, cardiovascular disease, diabetes and cancer, as well as a heightened risk of death. And this is regardless of one’s level of structured physical exercise, according to the authors of an article published [recently] in the British Journal of Sports Medicine.
The team from Stockholm, Sweden, says that sedentary behavior has become synonymous with lack of exercise, but that this is inaccurate and misleading. Rather, sedentary behavior should be defined as whole body muscular inactivity. Read more »