January 23rd, 2011 by Peggy Polaneczky, M.D. in Opinion, Research
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In a well done placebo-controlled study published in this week’s Journal of the American Medical Association (JAMA), use of escitalopram (Lexapro) reduced hot flashes in menopausal women.
Investigators enrolled 205 women, randomizing them to either Lexapro 10 mg or placebo, with instructions to increase to two pills a day if needed after four weeks. Lexapro users experienced about a 60 percent reduction in hot flash frequency over the eight-week study. About half ended up on the larger 20 mg daily dose by study’s end. The drug’s effect was apparent at about one week of use, and it was well tolerated.
As in almost studies of menopausal treatments, the placebo group also experienced a significant reduction in symptoms — about 40 percent — but the difference between placebo and drug groups was significant. Compared to placebo users, Lexapro users had a bigger rebound of symptoms when stopping their treatment, were more satisfied, and more likely to want to continue the study drug, another validation of the drug’s efficacy. Read more »
*This blog post was originally published at tbtam*
January 18th, 2011 by Peggy Polaneczky, M.D. in Better Health Network, Opinion
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Google is an amazing thing — it occasionally tosses you a link that lands you in an alternate universe of folks you’d never encounter in real life.
Like cattle ranchers. I’ve just spent the good part of an hour wandering their world — reading about their concerns (water, wolves, the economy), seeing how cattle breeding has changed (you pick a sire at Bullsemen.com, then do genomic profiling on your stock — did you know that cows bred for docility have more tender meat ?), and learning that ranchers are not immune to marketing from the world of scientific woo.
Check this out — it’s called SOP Life Vibration or “Serio Bio-Hygienization.” They’re selling it to farmers and ranchers in Europe and the U.S. as the latest and greatest answer to bacterial growth and odors in farm feed and bedding:
SOP products are formulated with the innovative Sirio Operating Process technology to improve the environment of the farm in a more effective and longer lasting way than current available means.
SOP® products are natural and scientifically tested. They are not enzymes, bacteria nor disinfectants. Using a process of “frequential bio-conditioning” they selectively favor the activity of the “beneficial” micro-organisms and create unfavorable conditions to inhibit the development of the “pathogenic” ones.
A 100% natural product. Through a bio-frequency method, SOP® is created with strategic wavelength and harmony. This same technology is comparable to the electronic systems used for radio broadcasting.
“100% natural,” “Bio-hygeinization,” ”Frequential bio-conditioning”…
I smell a woo. And that makes me nervous.
After all, I’m a meat eater. If someone’s putting something wacky into and around my food source, I want to know about it. So I decided it was worth my while to find out what the heck was in this SOP® stuff. Read more »
*This blog post was originally published at tbtam*
January 12th, 2011 by Peggy Polaneczky, M.D. in Better Health Network, News
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The media has been buzzing over recent reports of pregnancies occurring in women using Implanon, a single rod progestin-only contraceptive inserted under the skin of the upper arm and lasting for up to three years.
The headlines make it sound horrifying: “Hundreds Become Pregnant Despite Contraceptive Implanon” and “British Pregnancy Scare in UK Implicates Implanon.” I love how terminology can make something so common sound so frightening.
Actually, what happened was that 584 pregnancies occurred in Britain among about 1.3 million women using Implanon, for a failure rate of .04 percent. In other words, the method had an efficacy of over 99 percent. That’s a pretty effective contraceptive if you ask me.
But it should have been better than that
As good as it may seem, this failure rate is significantly higher than most of us would have expected based upon data from clinical trails of Implanon.
I recall being told at an Implanon insertion training just prior to its introduction in the U.S. that in fact, not a single pregnancy had been reported at that point among users of the device in clinical trails. This would put the method up there with sterilization and IUD in terms of efficacy.
So what happened?
How did Implanon go from perfect efficacy to something less than perfect? Read more »
*This blog post was originally published at tbtam*
January 7th, 2011 by Peggy Polaneczky, M.D. in Better Health Network, Health Tips
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Cute packaging and product placement in the checkout lane at Duane Reade will get you generic Tylenol for a price equivalent to $50 for 100 tabs, as opposed to $6 per 100 count in the usual package.
*This blog post was originally published at tbtam*
December 27th, 2010 by Peggy Polaneczky, M.D. in Better Health Network, Health Tips, News, Opinion, Quackery Exposed
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A spa in California is offering vaginal steam baths, in which spa-goers squat or sit on open stools over a tub of hot steam, as a cure-all for menstrual, digestion, and mood disorders:
The V-Steam: Inspired by an ancient ritual practiced for many years in Korea. The steam from the herbal tea rises and absorbs into your skin & orifice. This steaming treatment stimulates the production of hormones to maintain uterine health, aids regular menstrual cycles, helps correct digestive disorders while soothing the nervous system. The natural antibiotic and anti-fungal properties are said to help maintain internal health as well as keeping your skin looking young. (30 min: $50. Series of 6: $180.)
It’s a douche, folks. A $50 douche made with mugwort and 13 other herbs and having a fancy Korean name: Chai-Yok. True, the water gets up there as steam, and if you don’t squat just right over the steam bath, I imagine it may not get up there at all. But in the end, it’s a douche.
We docs strongly advise against douching since we know that women who do it have higher rates of vaginal and pelvic infections. Not to mention that the vaginal mucosa is highly-absorptive surface, meaning anything you put in there is likely to end up in the rest of your body. And so I ask: What herbs are they using, at what doses, and what side effects might they have? Not to mention what might be growing in those wooden tubs they have you squatting over? Read more »
*This blog post was originally published at tbtam*
