A year ago we wrote about a death of a San Jose teenager from poisoning by hydrogen sulfide gas, or H2S. At the time, I had hypothesized that the death might have been from an attempt at synthesizing methamphetamine gone awry.
But while one can mistakenly generate hydrogen sulfide gas from improper meth synthesis, I soon learned that intentional suicides with H2S is an increasing US trend imported from Japan. One can easily mix commonly-available consumer products to generate the gas and high enough concentrations can cause death. The gas acts in a manner similar to cyanide by binding to the heme in cytochrome c oxidase and inhibiting electron transport and ATP production by oxidative phosphorylation in the mitochondria. (Interestingly, small amounts of H2S are made in the body and is being investigated as a neurotransmitter and biological modulator.) Read more »
*This blog post was originally published at Terra Sigillata*