March 28th, 2011 by PJSkerrett in Health Tips, News
Tags: Cardiology, CHF, Death, Elizabeth Taylor, Health, Heart Failure, Heart Health, Women's Health
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The condition that took Elizabeth Taylor’s life affects millions of Americans.
Reports of Elizabeth Taylor’s death focused, as they should, on her life, not on her death from heart failure. But given how common this condition is—the American Heart Association says nearly 6 million Americans are living with heart failure and it kills about 300,000 each year—a little attention to it might be a good idea.
What is heart failure?
The term “heart failure” is a scary one, conjuring up images of a heart that is suddenly unable to work. In truth, it represents a gradual decline in the heart’s ability to pump enough blood to meet the body’s needs. As the heart weakens, all parts of the body suffer the consequences. Read more »
*This blog post was originally published at Harvard Health Blog*
March 26th, 2011 by DavidHarlow in Health Policy, News
Tags: Deidentification, HIPAA, Lawsuit, Legal, Patient Data, Prescription Drugs, Privacy, Walgreens
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Walgreens is being sued by customers who are not happy that their prescription information – even though it has been de-identified – is being sold by Walgreens to data-mining companies.
The data privacy and security concerns surrounding the transfer of de-identified data are significant. To “de-identify” what is otherwise protected health information under HIPAA, some outfits will simply strip data of 18 types of identifiers listed in federal regulations. However, the relevant regulation (45 CFR 164.514(b)(2)(ii)) also provides that this only works if “the covered entity does not have actual knowledge that the information could be used alone or in combination with other information to identify an individual who is a subject of the information.” Thus, the problem with this approach is that, these days, nobody can disclaim knowledge of the fact that information de-identified by removing this cookbook list of 18 identifiers may be re-identified by cross-matching data with other publicly-available data sources. There are a number of reported instances of this sort of thing happening. The bottom line is that our collective technical prowess has outstripped the regulatory safe harbor.
Is this the basis of the lawsuit brought against Walgreens? An objection to trafficking in health information that should remain private? No. The plaintiff group of customers is suing to share in the profits realized by Walgreens from trading in the de-identified data. Read more »
*This blog post was originally published at HealthBlawg :: David Harlow's Health Care Law Blog*
March 26th, 2011 by David Kroll, Ph.D. in News, Research
Tags: Anit-inflammatory, Cancer, epoxide, Herbal Supplement, Lei Gong Teng, Leukemia, Oncology, Thunder God Vine, Tripterygium Wilfordii Hook F, Triptolide, Tumor
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Thunder god vine may not be a useful herbal medicine but the compounds isolated from it are fascinating – if not as medicines, then most certainly as laboratory tools. Nature Chemical Biology recently published an article where a research team from Johns Hopkins, the University of Colorado at Boulder, and Drew University in New Jersey, has determined the molecular mechanism of action of triptolide, an unusual triepoxide compound from the plant.
Tripterygium wilfordii Hook F, or thunder god vine, is known as lei gong teng in Chinese traditional medicine and has a history of use as an anti-inflammatory herb. As with many traditional medicines, usage patterns do not necessarily indicate scientific validity. In fact, a Cochrane review published just last month on herbal therapies for rheumatoid arthritis indicated that the efficacy of thunder god vine was mixed. More concerning is that the herb had significant adverse effects in some trials, from hair loss to one case of aplastic anemia.
Nevertheless, the herb’s components have been studied since the 1970s for since they also appears to kill tumor cells in culture with nanomolar potency and have immunosuppresant activity in animal models. The group of the late natural products chemist at the University of Virginia, S. Morris Kupchan, first identified the unusual structures of triptolide and tripdiolide from Tripterygium wilfordii as described in this 1972 paper from the Journal of the American Chemical Society. Cytotoxic activity toward tumor cells in culture was used to guide the chemical fractionation of extracts. The unusual presence of three consecutive epoxides in the structures of both compounds led Kupchan to hypothesize later in Science that they target leukemia cells by covalent binding to cellular targets involved in cellular growth. Read more »
*This blog post was originally published at Science-Based Medicine*
March 25th, 2011 by Iltifat Husain, M.D. in News, Research
Tags: Literature Search, Mobile App, National Library of Medicine, NLM, PubMed, Search
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Recently, we reviewed six medical apps for the iPhone and iPad that promised mobile PubMed searches — an essential functionality since the PubMed.gov website is extremely difficult to view on a smart phone. As of last week, this is no longer the case. The U.S. National Library of Medicine (NLM) just launched a mobile friendly version of PubMed.gov last week.
The Web App they have created is currently in beta, and as of this publish date, if you go to PubMed.gov on your smart phone’s browser you will still be directed to the original non-mobile friendly website. However, if you point your phone’s browser to the following URL, http://www.ncbi.nlm.nih.gov/m/pubmed/, you are presented with the mobile version of the site.
The National Library of Medicine states the significant increase in mobile browsing for medical content is one of the key reasons they released this mobile web app. The folks at the NLM already have a plethora of mobile medical web apps available, such as the recently added MedLine Plus.
Continue on to see pictures of the PubMed app in action. Read more »
*This blog post was originally published at iMedicalApps*
March 24th, 2011 by RyanDuBosar in News
Tags: CDC, Death Rate, Disparities, Health Statistics, Heart Disease, Longevity, Mortality
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The U.S. age-adjusted death rate fell for the tenth consecutive year, to an all-time low of 741 deaths per 100,000 people in 2009, 2.3% lower than 2008, according to preliminary 2009 death statistics released by CDC’s National Center for Health Statistics.
The findings come from “Deaths: Preliminary Data for 2009,” which is based on death certificates from all 50 states, the District of Columbia and U.S. territories.
Life expectancy at birth increased to 78.2 years in 2009, up slightly from 78.0 years in 2008. Life expectancy was up two-tenths of a year for men (75.7 years) and up one-tenth of a year for women (80.6 years). Life expectancy for the U.S. white population increased by two-tenths of a year. Life expectancy for black men (70.9 years) and women (77.4 years) was unchanged in 2009. The gap in life expectancy between the white and black populations was 4.3 years in 2009, two-tenths of a year increase from the gap in 2008 of 4.1 years.
Read more »
*This blog post was originally published at ACP Internist*
