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Warfarin For Early Cancer Detection?

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In cancer treatment, detection of a tumor in an early stage markedly increases the chance of favorable outcomes.  
Can the much-aligned blood thinner, warfarin, occasionally help in early detection of cancer?

Few pharmacologic agents receive more bad press than warfarin.  Stories, which are too numerous to count, like “Did warfarin kill my father,” can be widely found on Internet forums, search engines, and are often quoted by reluctant patients — whose numerator of bad warfarin experiences is one.

It is true that warfarin has a narrow therapeutic window — a small difference between an effective dose and dangerous dose. Read more »

*This blog post was originally published at Dr John M*

Physical Activity For Weight Loss? Not For Most Middle-Aged Women

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Talk about a cruel trick of nature! A study funded by the National Institutes of Health (NIH) and published in the Journal of the American Medical Association (JAMA) shows that physical activity prevents weight gain in middle-aged and older women ONLY IF THEY ARE ALREADY AT IDEAL WEIGHT. Did you read that? It means that the recommended guidelines advocating 150 minutes of exercise a week isn’t sufficient to prevent weight gain in most middle-aged women.

The Harvard-associated researchers assessed weight changes associated with various levels of physical activity on 34,079 women who had been followed since 1992 in the Women’s Health Study. They stratified women as “inactive” (less than 150 minutes a week of moderate level physical activity), “intermediately active,” or “highly active” if they performed a high, strenuous level of activity. All three groups showed similar weight gain over a mean of 13 years of follow up. Read more »

*This blog post was originally published at EverythingHealth*

Doctor To Patient: “Do You Text And Drive?”

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It’s time to ask patients whether they text and drive. An important perspective piece from the New England Journal of Medicine urges doctors to include that question during preventive health exams. The data surrounding texting and driving is grim:

Although there are many possible distractions for drivers, more than 275 million Americans own cell phones, and 81% of them talk on those phones while driving. The adverse consequences have reached epidemic proportions. Current data suggest that each year, at least 1.6 million traffic accidents (28% of all crashes) in the United States are caused by drivers talking on cell phones or texting. Talking on the phone causes many more accidents than texting, simply because millions more drivers talk than text; moreover, using a hands-free device does not make talking on the phone any safer.

The author of the piece, Amy Ship from Boston’s Beth Israel Deaconess Hospital, says that doctors should update traditional preventive questions to keep up with the times.  The simple question, “Do you text while you drive?” is a way to start this important conversation. Read more »

*This blog post was originally published at KevinMD.com*

XXXtreme Calories Dishes: What Not To Eat

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It’s no secret that the U.S. has a weight problem and with chain restaurants serving up meals with thousands of calories in a single dish, it’s easy to understand why. Watch “CBS Doc Dot Com” to see which meals you should try to avoid — or at least share.


Watch CBS News Videos Online

Using Ultrasound To Zap The Brain Back Into Action

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Scientists at Arizona State University have developed a new method of non-surgical brain stimulation using pulsed ultrasound that enhances cognitive function in mice, and may one day be used to non-invasively treat patients with mental retardation, Alzheimer’s disease and other central nervous system (CNS) dysfunctions.

In intact motor cortex in mice, ultrasound was found to stimulate action potentials and elicit motor responses comparable to those only previously achieved with implanted electrodes and related techniques. It also activates meaningful brain wave patterns and the production of brain-derived neurotrophic factor (BDNF) in the hippocampus — one of the most potent regulators of brain plasticity. Read more »

*This blog post was originally published at Medgadget*

Latest Interviews

IDEA Labs: Medical Students Take The Lead In Healthcare Innovation

It’s no secret that doctors are disappointed with the way that the U.S. healthcare system is evolving. Most feel helpless about improving their work conditions or solving technical problems in patient care. Fortunately one young medical student was undeterred by the mountain of disappointment carried by his senior clinician mentors…

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How To Be A Successful Patient: Young Doctors Offer Some Advice

I am proud to be a part of the American Resident Project an initiative that promotes the writing of medical students residents and new physicians as they explore ideas for transforming American health care delivery. I recently had the opportunity to interview three of the writing fellows about how to…

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Latest Book Reviews

Book Review: Is Empathy Learned By Faking It Till It’s Real?

I m often asked to do book reviews on my blog and I rarely agree to them. This is because it takes me a long time to read a book and then if I don t enjoy it I figure the author would rather me remain silent than publish my…

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The Spirit Of The Place: Samuel Shem’s New Book May Depress You

When I was in medical school I read Samuel Shem s House Of God as a right of passage. At the time I found it to be a cynical yet eerily accurate portrayal of the underbelly of academic medicine. I gained comfort from its gallows humor and it made me…

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Eat To Save Your Life: Another Half-True Diet Book

I am hesitant to review diet books because they are so often a tangled mess of fact and fiction. Teasing out their truth from falsehood is about as exhausting as delousing a long-haired elementary school student. However after being approached by the authors’ PR agency with the promise of a…

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