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Biotech And Life Sciences Grant Program: Only A Few Crumbs To Go Around?

crumbs Biotech Grant Program: Are a Few Crumbs Better Than No Crumbs At All?After assuming control of the House in the mid-term elections, Republicans vowed to eviscerate the Affordable Care Act, the health reform law signed by the “Big O” last March. Thank heavens, therefore, that the Boehners were too busy congratulating themselves to even notice those federal helicopters dumping $1 billion in cash on some needy biotech companies just as the election results were being tallied.

Yep, it happened. Federal disbursements in the form of grants and tax credits were made last week, as required by a provision in the reform law known as the Qualifying Therapeutic Discovery Project Program. According to the terms of this program, biotech and life sciences companies with less than 250 employees could apply for federal funds to cover research costs they had incurred in the last two years, so long as the research focused on the prevention, diagnosis, and treatment of chronic diseases. Read more »

*This blog post was originally published at Pizaazz*

Can The Expiration Date Of Harvested Organs Be Extended?

Currently, once a donated organ has been harvested it only has a few hours on ice before it “expires.” Lengthening this time period would be an incredible breakthrough that would allow patients in a wider area to potentially receive a transplant and also it would reduce some of the insanity surrounding the time pressures of organ transplantation.

One proposed method of extending an organ’s shelf life is to alter the internal cell biology to allow cells to live longer at lower temperatures. The State University of New Jersey Rutgers-Camden just received a $385,419 grant from the NIH to study an enzyme system, AMP phosphatase, and how it can potentially create cold-tolerant Drosophila. The enzyme was originally identified in ice worms as the key enzyme that allows them to survive in glaciers. The researchers hope that if they are able to utilize this enzyme system to create a cold-tolerant fruit fly, then they would be able to apply that knowledge to donated organs. Read more »

*This blog post was originally published at Medgadget*

Do You Have A “Good” Heart?

I saw a prescient story that linked antagonistic personality traits and cardiovascular risk. It was simply impossible to ignore. Low hanging fruit, no doubt.

The article highlights an NIH-sponsored study [published in the August 16th journal Hypertension] that looked at the effects of antagonistic traits — agreeableness, per se — on heart health. Yes, you read it right — agreeableness. To quantify agreeableness, the researchers used a personality questionnaire which included six traits: Trust, straightforwardness, altruism, compliance, modesty, and my favorite…tender-mindedness.

Your hypothesis is probably right: People who were distrustful, cynical, manipulative, self-centered, and quick to express anger fared worse. But please don’t dismiss this as just another mundane study proclaiming the risks of an angry personality. The specifics of the findings and their implications really hit hard. Read more »

*This blog post was originally published at Dr John M*

More On The False Claims Of A Cancer Researcher At Duke

This is not good. Not good at all.

Recently Paul Goldberg of The Cancer Letter reported on an investigation into Duke cancer researcher Anil Potti, M.D., and claims made that he was a Rhodes Scholar in Australia. The misrepresentation was made on grant applications to National Institutes of Health (NIH) and the American Cancer Society (ACS).

The Cancer Letter, a $375 per year go-to newsletter on cancer research, funding, and drug development, has made this issue free at this PDF link.

News & Observer higher education reporter Eric Ferreri has a nice overview of the situation. Potti has been placed on administrative leave by Duke, and the ACS has suspended payments on his grant and initiated their own investigation. Read more »

*This blog post was originally published at Terra Sigillata*

Physical Activity For Weight Loss? Not For Most Middle-Aged Women

Talk about a cruel trick of nature! A study funded by the National Institutes of Health (NIH) and published in the Journal of the American Medical Association (JAMA) shows that physical activity prevents weight gain in middle-aged and older women ONLY IF THEY ARE ALREADY AT IDEAL WEIGHT. Did you read that? It means that the recommended guidelines advocating 150 minutes of exercise a week isn’t sufficient to prevent weight gain in most middle-aged women.

The Harvard-associated researchers assessed weight changes associated with various levels of physical activity on 34,079 women who had been followed since 1992 in the Women’s Health Study. They stratified women as “inactive” (less than 150 minutes a week of moderate level physical activity), “intermediately active,” or “highly active” if they performed a high, strenuous level of activity. All three groups showed similar weight gain over a mean of 13 years of follow up. Read more »

*This blog post was originally published at EverythingHealth*

Latest Interviews

IDEA Labs: Medical Students Take The Lead In Healthcare Innovation

It’s no secret that doctors are disappointed with the way that the U.S. healthcare system is evolving. Most feel helpless about improving their work conditions or solving technical problems in patient care. Fortunately one young medical student was undeterred by the mountain of disappointment carried by his senior clinician mentors…

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How To Be A Successful Patient: Young Doctors Offer Some Advice

I am proud to be a part of the American Resident Project an initiative that promotes the writing of medical students residents and new physicians as they explore ideas for transforming American health care delivery. I recently had the opportunity to interview three of the writing fellows about how to…

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Latest Book Reviews

Book Review: Is Empathy Learned By Faking It Till It’s Real?

I m often asked to do book reviews on my blog and I rarely agree to them. This is because it takes me a long time to read a book and then if I don t enjoy it I figure the author would rather me remain silent than publish my…

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The Spirit Of The Place: Samuel Shem’s New Book May Depress You

When I was in medical school I read Samuel Shem s House Of God as a right of passage. At the time I found it to be a cynical yet eerily accurate portrayal of the underbelly of academic medicine. I gained comfort from its gallows humor and it made me…

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Eat To Save Your Life: Another Half-True Diet Book

I am hesitant to review diet books because they are so often a tangled mess of fact and fiction. Teasing out their truth from falsehood is about as exhausting as delousing a long-haired elementary school student. However after being approached by the authors’ PR agency with the promise of a…

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