July 15th, 2011 by Linda Burke-Galloway, M.D. in Health Tips, Research
Tags: Back, Blood Flow, Blood Pressure, Cardiac Output, CO, Dr. Linda Burke-Galloway, Fetal Complications, Inferior Vena Cava, IVC, Oxygen Suppy, Pregnant Women, Sleep, Sleeping Position, Stillbirth, Supine Hypotensive Disorder, Uterus
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A little knowledge is dangerous; especially when it relates to medicine. A recent article in the British newspaper, Daily Mirror discussed a medical study that attempted to prove there was a link between pregnant women’s sleeping positions and stillbirth. The author is of the opinion that the study was small and biased and therefore “there is a serious need for more research before we’re in a strong position to make ¬any recommendations.” Obviously this author has limited knowledge about the cardiovascular system of a pregnant woman.
Our organs and tissues require oxygen to function. Without it, they essentially die. Blood from the lower part of our body flows back to the heart where it receives oxygen, compliments of a large blood vessel called the Inferior Vena Cava (IVC). The inferior vena cava is a large, thin-walled blood vessel located near the spine. As the pregnant uterus becomes enlarged, it can press against the IVC and reduce the amount of its blood flow. Why is that not good? Because it reduces the circulating blood flow in the body that is commonly known as our cardiac output (CO). When the pregnant uterus squeezes the IVC and reduces cardiac output, a woman might feel dizzy and even faint. Her blood supply of oxygen is reduced and the unborn baby’s is as well. When a pregnant woman in her early or late third trimester feels faint after lying flat on her back, the syndrome is called Supine Hypotensive Disorder. Her blood pressure has dropped because her cardiac output has dropped. The heart can only pump out what comes into it, so less blood into the heart means less blood going out of the heart and the patient feels faint. How is this avoided? Read more »
*This blog post was originally published at Dr. Linda Burke-Galloway*
July 12th, 2011 by Toni Brayer, M.D. in Opinion, Research
Tags: Anti-depressants, Asperger's Sydnrome, Autism, link, Pediatrics, Psychiatry, SSRIs, Uterine Environment
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Two news events got people talking recently. One was that Casey was deemed not guilty of killing little daughter Caylee ( “O.J. all over again”, I heard repeatedly). I must admit I was rather surprised….
The second was the results of two new studies that were published in the Archives of General Psychiatry. One of them stated that environmental factors during pregnancy might contribute as much as genetics in the development of autism spectrum disorders. The 2nd study conducted by Kaiser Permanente Northern California found a 3 times higher risk of autism if the mother took antidepressants in the first trimester of pregnancy.
With the incidence of autism disorders increasing over time to the current range of 3-6 per 1,000 births, these studies are of interest to millions of parents and professionals. Autism affects boys at a rate of three times more than girls, and is usually detected by the age of 3. The cause has been maddeningly unknown.
While genes certainly play a part (as they do in most every disorder) other theories and assertions have been disproven. It certainly does not have anything to do with “poor mothering” or “lack of maternal bonding”. Those theories did more harm than bloodletting in the 19th century! The link between autism and vaccines has been thoroughly debunked. If you believe in science and research, you must believe that vaccines are not the cause and finally leave that one in the dust. Read more »
*This blog post was originally published at EverythingHealth*
July 11th, 2011 by IsisTheScientist in Opinion, Research
Tags: Collaboration, Dangers, Human Nature, Labs, Psychology, Science, Stealing Data, Time Constraints
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Yesterday I went to go see my friend, the recently infrequently-mentioned Dr. Buttercup. When I first came to MRU, Dr. Buttercup was gracious enough to allow me to share lab space with him. That, coupled with our mutual love of beer and cake, meant that we saw each other quite frequently. Now that I have moved into other laboratory digs and find myself full of people, I see less of Dr. Buttercup and am the recipient of far less of his wisdom. It’s a shame. I miss that dude.
Then again, as soon as that guy received a grant score that someone told him was “fundable”, he became insufferable. Show off.
But, I digress. I saw Dr. Buttercup yesterday about a different matter and we got to discussing the idea of collaboration. He shared the notion that, as an Assistant Professor, collaboration is one of the funnest things he does. It’s also potentially one of the most dangerous because it robs your time without real reward. Still, brainstorming new experiments is fun and sometimes that additional effort on someone else’s grant pays the bills.
This made me think that the same is true for postdoc-level scientists and made me think about some collaborations I got myself into once upon a time. You see, when you’re a newly-minted, grown-up scientist, you’re on top of the world. Perhaps you start to feel like an expert in something and, perhaps, you’re enthusiastic to show the folks around you how good you are at what you do.
Don’t do it. Read more »
*This blog post was originally published at On Becoming a Domestic and Laboratory Goddess*
July 10th, 2011 by RyanDuBosar in Research
Tags: E-prescribing, EHRs, Electronic Medical Records, Error Rate, Hand-Written, Medical Error, Patient Safety, Prescriptions
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About 10% of computer-generated prescriptions included at least one error, of which a third had potential for harm, researchers reported in the Journal of the American Medical Informatics Association.
This errors rate matched that of handwritten prescriptions, deflating at least one reason for the federal government’s incentives to switch providers to e-prescribing. The government had provided incentives for switching to e-prescribing; those turned to penalties for not doing so on July 30.
Researchers conducted a retrospective cohort study of 3,850 e-prescriptions received by a commercial outpatient pharmacy chain across three states over four weeks in 2008. A panel reviewed them for medication errors, potential adverse drug events, and rate of prescribing errors by type and by prescribing system. Read more »
*This blog post was originally published at ACP Internist*
July 8th, 2011 by John Di Saia, M.D. in Research
Tags: Botox, Breast Implants, Incidence, Liposuction, Plastic Surgery, Prevalence, Rise In Popularity, Statistics, Teen
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The American Society of Aesthetic Plastic Surgery publishes statistics every year indicating which cosmetic operations are on the rise. A journalist at the OC Register asked a group of plastic surgeons why this might be. Being that I am opinionated (why do you think I blog here,) I figured I’d take a shot at some of these:
I. Statistic: TEENS – Nosejobs and Otoplasty (commonly referred to as “ear pinning”) on the rise
Dr D: Part of the development of the teen psyche involves becoming aware of social norms. As they do this, they also become aware of differences and develop standards of beauty. Many of these teen nose jobs are justified as medically-needed, but appearance usually factors in. Otoplasty is a similarly social operation.
II. Statistic: YOUNG ADULTS – Breast implants. Ages 19-34. 166,000 a year. (ASAPS)
Dr D: “Beauty standards” are important motivators here as well. Young adults in the workplace (and social groups) see those around them doing these things and often being complimented. Some of these patients may also be seeking after childbirth “body repair.”
III. Statistic: EARLY MIDDLE AGE – Liposuction. Ages 35-50. 143,000 a year. (ASAPS)
Dr D: A slowing metabolism in this age group combined with more involved work schedules (with increased sedentary time) equals increased trouble “holding back the fat.” Liposuction is easy and can help with that. Add some post-pregnancy issues here as well.
IV. Statistic: YOUNG ADULTS – Botox. Ages 19-34. 371,000 a year. (ASAPS)
Dr D: The fad of Botox use in the really young is an advertising phenomenon as there is no good reason for young people to do this other than to “feel” hip.
My opinions of course. 
*This blog post was originally published at Truth in Cosmetic Surgery*