British scientists announced that attention-deficit/hyperactivity disorder (ADHD) has been linked to deleted or duplicated DNA segments (copy number variants), which leads to developmental difference in the brains of children with the condition.
Researchers scanned genomes of 366 children with ADHD and compared them with 1,047 unrelated, ethnically matched control subjects. They reported full results in The Lancet.
Rare copy number variants were almost twice as common in children with ADHD compared to the other children. Researchers commented to Reuters that there was a significant overlap between copy number variants found in ADHD and elements of the genome linked to autism and schizophrenia, specifically in a region on chromosome 16.
*This blog post was originally published at ACP Internist*
The event, coinciding with ADD/ADHD Awareness Week, was a panel discussion about the impact ADHD has on our society. It was sponsored by Shire, in partnership with the Entertainment Industries Council (EIC) and the Lab School of Washington [Disclosure: I received a stipend for covering the event.]
Below are interviews Rob and I did with some of the panelists.
Kevin Pho interview with Michele Novotni, Ph.D., ADHD Expert and Former Attention Deficit Disorder Association (ADDA) President:
The man who twirled with rose in teeth
Has his tongue tied up in thorns
His once expanded sense of time and
Space all shot and torn
See him wander hat in hand –
“Look at me, I’m so forlorn –
Ask anyone who can recall
It’s horrible to be born!
– Bruce Cockburn, from song “Shipwrecked at the Stable Door”
I found the discussion around my recent post about treating colds very interesting. Sick people come to the office to find out how sick they are. Most people don’t want to be sick, and when they are sick they want doctors to make them better.
Most people.
Some people want to be sick, and some doctors want to make people sick. I am not talking about hypochondriacs — people who worry that they may have disease and become fixated on being sick. I am not talking about malingerers — people who pretend to be sick so they can get medications. I am talking about the slippery slope of defining disease. Read more »
Attention-deficit/hyperactivity disorder (ADHD) is probably overdiagnosed by physicians. In the lay public, the term is often used jokingly to describe the common feeling of distraction we experience in a world filled with interruptions. With a constant stream of text messages, Facebook updates, TV commercials, and fast-paced Twittering, there’s little wonder that we all feel frazzled at times.
But the occasional experience of jangled nerves is not a proper basis for a diagnosis of ADHD. Unfortunately, there has been great confusion between the actual disorder, and its misuse as a label for simply feeling distracted.
So to help set the record straight and to tease out fact from fiction, I’ll be attending a forum on Capitol Hill with my co-bloggers Dr. Kevin Pho and Dr. Rob Lamberts.
If you’re in the DC area, please come and join us in person. If you’d like to view some of the event via the Internet, we’ll be conducting live interviews with the speakers on Ustream. You can join the conversation by asking your questionsin real time in the chat room starting at 2:00PM (EST) on Thursday, September 16, 2010. Please save the Ustream link to join the conversation: http://www.ustream.tv/channel/fact-or-fiction-adhd-in-america.Read more »
It is summer camp season for kids and well-run camps require a medical history and record of prescription medications that the child is taking. One prestigious camp for teens (ages 11 to 19 — average camper is 16) in Southern California recently had 153 residential teenagers. These kids come from California and other states across the U.S. Fifty percent come from out of state and a number of campers each week are international.
Okay, so far so good. Healthy teens getting together for a week of learning and fun. Here is the shocker! I was amazed to learn that almost 25 percent of these kids are on prescription medication. Can it be that we are overmedicating teens?
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It is summer camp season for kids and well-run camps require a medical history and record of prescription medications that the child is taking. One prestigious camp for teens (ages 11 to 19 — average camper is 16) in Southern California recently had 153 residential teenagers. These kids come from California and other states across the U.S. Fifty percent come from out of state and a number of campers each week are international.
